Toll signaling pathways in the innate immune response.

By Kathryn V. Anderson. Current Opinion in Immunology, 2000

678 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/c59916e6152af0ce31a14568fe1315c75bc7e92d

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In Immunology

1. Shizuo Akira
2. R. Medzhitov
3. K. Takeda
4. S. Ghosh
5. Taro Kawai
6. T. Kaisho
7. O. Takeuchi
8. S. Rivest

Citations in the corpus

• Toll-like receptors in the induction of the innate immune response (2000, background): “The activation of dToll induces an anti-fungal peptide, drosomycin, whereas the ligation of 18-wheeler induces an antibacterial peptide, attaci”
• Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity. (2001, background): “In Drosophila, three NF-κB homologs named Dorsal, Dif, and Relish have been identified and characterized (5, 6).”
• Structural basis for signal transduction by the Toll/interleukin-1 receptor domains (2000, neutral): “gif" NDATA ITEM> ]> Toll-like receptors (TLRs) and the interleukin-1 receptor superfamily (IL-1Rs) are integral to both innate and adaptive immunity for host defenc”
• Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 41 (2002, background): “M ulticellular organisms have sentinel receptors that distinguish conditions of well-being from conditions of disease (1, 2).”
• Broad Expression of Toll‐Like Receptors in the Human Central Nervous System (2002, background): “Both IL-1R and TLRs induce signal transduction pathways leading predominantly to activation of the transcription factor NF-kB (3–6), a key regulator of inflammatory responses (7).”
• Inflammatory and immune pathways in the pathogenesis of periodontal disease (2014, background): “include toll-like receptors and related proteins that regulate apoptosis, inflammation and immune responses (3, 95) (Fig.”
• Toll-like receptors: critical proteins linking innate and acquired immunity (2001, background): “Mammalian Toll-like receptors Toll receptors are type I transmembrane proteins that are evolutionarily conserved between insects and human”
• Are innate immune signaling pathways in plants and animals conserved? (2005, background): “Study of conserved TLR signaling pathways has served as a paradigm for insights that can be gained due to evolutionary conservation of innate immune signaling component”
• Toll-like receptors and innate immunity (2001, background): “html?FBgn0003717"> Toll , was discovered as a maternal-effect gene that functions in a pathway that controls dorsoventral axis formation in fruitfly embryo”
• Innate immunity: the missing link in neuroprotection and neurodegeneration? (2002, background): “Innate immunity Host organisms detect the presence of infection by recognizing specific elements produced by microorganism”
• Innate immune recognition. (2002, background): “MyD88: an adapter that recruits IRAK to the IL-1 receptor complex.”