Learning enhances adult neurogenesis in the hippocampal formation

By E. Gould, A. Beylin, P. Tanapat, Alison J. Reeves, T. Shors. 1999

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Citations in the corpus

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, background): “Hippocampus-dependent learning is one of the major regulators of hippocampal neurogenesi”
REMIND Your Neural Network to Prevent Catastrophic Forgetting (2019, background): “During waking hours, the hippocampus learns quickly, which may be facilitated using neurogenesis [30].”
Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood (2006, background): “CNS-specific T cells contribute to spatial learning Recent findings point to an association between adult neurogenesis and certain hippocampal activitie”
Granule-Like Neurons at the Hilar/CA3 Border after Status Epilepticus and Their Synchrony with Area CA3 Pyramidal Cells: Functional Implications of Seizure-Induced Neurogenesis (2000, background): “Thus, changes in such diverse factors as stress (Cameron and Gould, 1994; Gould et al., 1997, 1998), learning (Gould et al., 1999), exercise (van Praag et al., 1999), environmental stimulation (Kempermann et al., 1998a,b), neurotransmitters and hormones (Cameron et al., 1995; Brezun and Dazsuta,…”
Enriched Odor Exposure Increases the Number of Newborn Neurons in the Adult Olfactory Bulb and Improves Odor Memory (2002, background): “…number of adultgenerated neurons in birds and rodents, presumably by enhancing cell survival (Barnea and Nottebohm, 1994; Kempermann et al., 1997; Gould et al., 1999; van Praag et al., 1999) and facilitating the integration of adult-generated cells into the existing neural circuitry (Gould et…”
Neurogenesis in the adult brain: death of a dogma (2000, background): “studied the influence of specific learning experiences on new neurons in the dentate gyrus of adult rat”
Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. (2004, background): “Speed makes it possible to integrate information across the highly distributed neural networks that underlie higher cognitive functions [10,14,82,97,155,222].”
Extreme sensitivity of adult neurogenesis to low doses of X-irradiation. (2003, background): “Given the apparent relationship between hippocampal neurogenesis and associated memory formation (19), the responses seen here may have an important impact in our understanding of radiation-induced cognitive impairment.”
New neurons in the dentate gyrus are involved in the expression of enhanced long‐term memory following environmental enrichment (2005, methodology): “For example, training on hippocampaldependent learning tasks specifically enhances survival of adultgenerated neurons in the rat dentate gyrus (Gould et al., 1999a) and, conversely, the reduction of neurogenesis by a cytostatic drug impairs associative hippocampal-dependent, but not…”
Apoptosis, neurogenesis, and information content in Hebbian networks (2005, background): “Adult neurogenesis occurs in man as well as other mammalian species (Gould et al. 1999; Makakis and Gage 1999).”
Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells (2006, background): “However, a few studies report lowlevel constitutively occurring neurogenesis in specific regions of the neocortex of adult primates (Gould et al. 1999c, 2001) and in the visual cortex of adult rat (Kaplan 1981).”
Astrocytes Give Rise to New Neurons in the Adult Mammalian Hippocampus (2001, background): “The function of neurogenesis in the hippocampus has been correlated with learning and memory (Barnea and Nottebohm, 1995; Kempermann et al., 1997; Gould et al., 1999; Shors et al., 2001).”
Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons (2007, background): “Interrelated Processes It has previously been shown that training in a water maze increases the survival of newborn neurons that were produced 1 wk before the start of the training [19,26].”