New neurons in the dentate gyrus are involved in the expression of enhanced long‐term memory following environmental enrichment

By E. Bruel-Jungerman, S. Laroche, C. Rampon. 2005

528 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Developmental Neuroscience, Neurology

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Citations in the corpus

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, background): “In addition, environmental enrichment improves performance in learning and memory tasks such as the MWM and object recognition test”
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons (2008, result): “Similar distinctions have been reported with respect to the role of adult-generated neurons in recognition memory: systemic treatment with an antimitotic reversed enhancement of performance on the novel-object preference task after environmental enrichmen”
Assessment of positive emotions in animals to improve their welfare. (2007, background): “Consequently, coping with enriched environments requires activity and exercise, and such environments favor hippocampal neurogenesis and synaptic plasticity [82,83].”
Methylazoxymethanol acetate does not fully block cell genesis in the young and aged dentate gyrus (2005, result): “This level of reduction was in the range of that obtained recently following treatment with 5 mg ⁄ kg of MAM (Shors et al., 2001; Bruel-Jungerman et al., 2005), and was less pronounced than that reported previously for 7 mg ⁄ kg of MAM (Shors et al., 2001, 2002).”
Structural Plasticity and Hippocampal Function (2010, background): “…the depletion of newborn cells has been achieved pharmacologically by systemic administration of the antimitotic agent methylazoxymethanol (MAM; Bruel-Jungerman et al. 2005, Shors et al. 2001b) or the DNA-alkylating agent temozolomide (TMZ; Garthe et al. 2009) as well as by central infusion of…”
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. (2009, background): “Furthermore, another recent study showed that the improved object recognition performance associated with environmental enrichment is dependent on the generation of new neurons (Bruel-Jungerman et al. 2005).”
Mechanisms and functional implications of adult neurogenesis. (2008, unknown): “However, defective object recognition memory was not detected in irradiated or MAM-treated rats in a simpler context (Bruel-Jungerman et al., 2005; Madsen et al., 2003).”
Adult-born hippocampal neurons are more numerous, faster-maturing and more involved in behavior in rats than in mice (2009, background): “…function by 4 weeks of age (Snyder et al., 2005; Winocur et al., 2006; Wojtowicz et al., 2008) and, in several cases, as young as 2–3 weeks of age (Shors et al., 2001; Snyder et al., 2001; Shors et al., 2002; Madsen et al., 2003; Schmidt-Hieber et al., 2004; Bruel-Jungerman et al., 2005).”
Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways (2006, background): “…produced an overall increase in the amount of neurogenesis, which could be observed in both rats and mice (Paylor et al., 1992; Kempermann et al., 1997; Pham et al., 1999; van Praag et al., 1999a,b; Auvergne et al., 2002; Frick and Fernandez, 2003; Cao et al., 2004; Bruel-Jungerman et al., 2005).”
Environmental enrichment and neurogenesis: from mice to humans (2015, background): “In some cases, MAM treatment of rats during EE impaired performance in object recognition memory and a trace fear conditioning paradigm, but not contextual fear conditioning or spatial navigation learning in the MWM [41,42].”
Modification of hippocampal circuitry by adult neurogenesis (2012, background): “MAM treatment also prevents the long-term memory improvement normally induced by environmental enrichment (Bruel-Jungerman et al., 2005).”
Long-Term Potentiation Enhances Neurogenesis in the Adult Dentate Gyrus (2006, methodology): “Several reports have demonstrated that behavioral activity such as environmental enrichment (Kempermann et al., 1997; Bruel-Jungerman et al., 2005), physical exercise (van Praag et al.”
Experience-Specific Functional Modification of the Dentate Gyrus through Adult Neurogenesis: A Critical Period during an Immature Stage (2007, background): “Considering the suggested role of adult new neurons in hippocampus-dependent forms of learning and memory (Shors et al., 2001, 2002; Bruel-Jungerman et al., 2005; Snyder et al., 2005; Winocur et al., 2006), this experience-specific functional modification might be a mechanism by which new neurons…”
Dopaminergic Modulation of Cortical Inputs during Maturation of Adult-born Dentate Granule Cells (2011, background): “Although the exact contribution of newly born DGCs to hippocampal physiology and behavior remains to be clarified, increasing lines of evidence have suggested that they are involved in learning and memory as young as 2– 4 weeks of age (Shors et al., 2001; Bruel-Jungerman et al., 2005; Snyder et al.,”