Embryonic stem cells

By H. Rippon, A. Bishop. Cell Proliferation, 2004

1,193 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/6bc136c09e1d899dfc94451a50b7e76de922a539

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Citations in the corpus

Naive and primed pluripotent states. (2009, background): “Lif activates the transcription factor Stat3, which inhibits ESC differentiation and promotes viability (Smith, 2001).”
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo (2009, background): “The relationship between pluripotent cells that exist transiently in the mammalian embryo and immortal ES cells in culture has not been fully defined (Gardner and Brook, 1997; Smith, 2001).”
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment (2007, background): “These properties make ES cells a unique system in which to study developmental decisions and differentiation (Kouskoff et al., 2005; Nishikawa et al., 1998; Niwa et al., 2005; Smith, 2001a; Tada et al., 2005), and also a promising tool for biotechnological and biomedical applications (Keller, 2005).”
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. (2003, neutral): “In serum- free cultures, however, LIF is insufficient to block neu- tion capacity (Smith, 2001b).”
Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation (2005, background): “The ability of hESCs to differentiate spontaneously has been well documented (Itskovitz-Eldor et al., 2000; Reubinoff et al., 2000; Schuldiner et al., 2000; Levenberg et al., 2002; Xu et al., 2002).”
Embryonic stem cell differentiation: emergence of a new era in biology and medicine. (2005, background): “The reader is referred to other recent reviews that provide additional details for many of the subjects covered here (Kyba and Daley 2003; Nir et al. 2003; Hornstein and Benvenisty 2004; Lang et al. 2004; Pera and Trounson 2004; Rippon and Bishop 2004; West and Daley 2004).”
Human embryonic stem cells express a unique set of microRNAs. (2004, background): “They are characterized by nearly unlimited self-renewal in an undifferentiated state under defined culture conditions while retaining differentiation capacity (Evans and Kaufman, 1981; Martin, 1981; Smith, 2001).”
The Human Cell Atlas (2017, neutral): “Finally, we will likely learn about the nature of stable states: while we often think of stable states as discrete attractor basins (Waddington, 1957), there may also be troughs that reflect a continuous spectrum of stable states (e. g., the ratio of two processes may vary across cells, but are stab”
The Hippo signaling pathway in stem cell biology and cancer (2014, neutral): “signals were shown to maintain mouse ESCs in an undifferentiated, pluripotent state, whereas human ESCs require FGF, BMP, and TGF-b/activin [82–84].”
Bone tissue engineering: state of the art and future trends. (2004, neutral): “When kept in culture murine (rodent) ES cells remain undifferentiated in the presence of leukaemia inhibitory factor (LIF) or, in alternative, when cultured with a feeder layer of murine embryonic fibroblasts (MEF) [195].”
Signalling, cell cycle and pluripotency in embryonic stem cells. (2002, background): “Tom Burdon, Austin Smith and Pierre Savatier 80 Mitelman, F. (2000) Recurrent chromosome aberrations in cancer. Mutat. Res. 462, 247–253 81 Elliott, B. and Jasin, M. (2002) Double-strand breaks and translocations in cancer. Cell. Mol. Life Sci. 59, 373–385 82 Sachs, R.K. et al. (1997) Proximity effe”