Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies.

By G. Williamson, Claudine Manach. American Journal of Clinical Nutrition, 2005

1,514 citations recorded by the source corpus.

Subfields: Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/5cca297056e360ad6a6aac02e71a800b87cb90fb

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Citations in the corpus

Globe artichoke as a functional food (2010, neutral): “In recent years, several epidemiological studies showed that the consumption of fruits and vegetables, typical of the Mediterranean diet, is associated with a decrease in the risk of cancer and cardiovascular diseases [2].”
A Review of the Antioxidant Mechanisms of Polyphenol Compounds Related to Iron Binding (2009, background): “The general bioavailability of polyphenol compounds, not related to iron, is an active research area [205, 206], but is beyond the scope of this review.”
Flavonoid Bioavailability and Attempts for Bioavailability Enhancement (2013, background): “Quercetin aglycone or its glycosides are generally not found in plasma but its glucuronic acid, sulfate or methyl conjugates were exclusively present in plasma [56,57].”
Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. (2005, background): “[53] Williamson G, Manach C.”
Bioavailability of the Polyphenols: Status and Controversies (2010, background): “This situation may improve in the future, for example, with the use of isogenic lines of onions that differ only in their quercetin contents [50], allowing comparisons between groups consuming the same food but with different polyphenol contents [5].”
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. (2005, background): “In addition, the consumption of proanthocyanidin-rich foods, such as cocoa, red wine, or grape seed extracts, has been shown to increase the plasma antioxidant capacity, to have positive effects on vascular function, and to reduce platelet activity in humans (97).”
Polyphenols: antioxidants and beyond. (2005, neutral): “tus of different oxidative stress biomarkers (6).”
Identification of the 100 richest dietary sources of polyphenols: an application of the Phenol-Explorer database (2010, background): “The total polyphenols concentration of a food is unlikely to fully explain any associated health effects because of the large differences in the bioavailability and biological activity of individual polyphenols (Manach et al., 2005; Williamson and Manach, 2005).”
The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility (2016, background): “In the intestinal mucosa, only aglycones and some glucosides can be absorbed [137].”
Quercetin, Inflammation and Immunity (2016, background): “Quercetin is also found in medicinal botanicals, including Ginkgo biloba, Hypericum perforatum, and Sambucus canadensis [6] [7] [8] .”
Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials. (2008, background): “1 mol/L to 100 mol/L, whereas physiologic concentrations will rarely reach 10 mol/L (61).”
Phenol-Explorer: an online comprehensive database on polyphenol contents in foods (2010, background): “Dietary polyphenols differ widely in their physico-chemical properties, bioavailability, biological properties and health effects (5,6).”
Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action (2010, background): “Many studies have reported the bioavailability of polyphenols in the systemic circulation [188-191].”
Nutritional Quality and Health Benefits of Okra (Abelmoschus esculentus): A Review (2015, background): “These properties, along with the high content of carbohydrates, proteins, glycol-protein, and other dietary elements enhance the importance of this foodstuff in the human diet [12, 40].”