The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility
By T. Ozdal, D. Sela, Jianbo Xiao, D. Boyacioğlu, Fang Chen, E. Çapanoğlu. Nutrients, 2016
684 citations recorded by the source corpus.
As of late, polyphenols have increasingly interested the scientific community due to their proposed health benefits. Much of this attention has focused on their bioavailability. Polyphenol–gut microbiota interactions should be considered to understand their biological functions. The dichotomy between the biotransformation of polyphenols into their metabolites by gut microbiota and the modulation of gut microbiota composition by polyphenols contributes to positive health outcomes. Although there are many studies on the in vivo bioavailability of polyphenols, the mutual relationship between polyphenols and gut microbiota is not fully understood. This review focuses on the biotransformation of polyphenols by gut microbiota, modulation of gut microbiota by polyphenols, and the effects of these two-way mutual interactions on polyphenol bioavailability, and ultimately, human health.
Subfields: Biochemistry, Molecular Biology, Pathology and Forensic Medicine
View Paper: https://www.semanticscholar.org/paper/8bd5223dbac97c528a5555ee8e12cb9a2a723d24
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Citations in the corpus
- Natural polyphenols: An overview (2017, background): “Flavonoids found in cocoa and soy present favorable outcomes on cardiovascular disease,([26]) and others are not as efficient.([27,28]) The antioxidant potential of polyphenols is related to the cardioprotective properties of such compounds; because reduced blood pressure,([29,30]) with improved fun”
- The Effects of Vegetarian and Vegan Diets on Gut Microbiota (2019, background): “The interaction of polyphenols and gut microbiota is bidirectional (90, 91).”