Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae.

By C. Lupp, Marilyn L. Robertson, Mark E. Wickham, I. Sekirov, O. Champion, Erin C. Gaynor, B. B. Finlay. Cell Host and Microbe, 2007

1,226 citations recorded by the source corpus.

Subfields: Food Science, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/598c10db1db8e557f5c70896abae185c649f25e1

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Citations in the corpus

Defining dysbiosis and its influence on host immunity and disease (2014, background): “Klebsiella pneumonia and Proteus mirabilis, both members of the Enterobacteriaceae family, also expanded to induce colitis within T-bet−/− X Rag2−/− mice (Garrett et al., 2007).”
Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease (2017, background): “Consistently, the relative luminal abundance of Enterobacteriaceae dramatically increased in either chemical -induced or genetic mouse models of IBD (135, 136, 142).”
Role of the Microbiota in Immunity and inflammation (2014, background): “In particular, γ-proteobacteria dominance has emerged as a hallmark of acute mucosal infections and enhanced pathology (Benson et al., 2009; Craven et al., 2012; Egan et al., 2011; Heimesaat et al., 2006; Lupp et al., 2007; Molloy et al., 2013; Raetz et al., 2012; Stecher et al., 2007).”
Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications. (2012, background): “Mice lacking immune modulators such as interleukin-10 or nuclear factor k B have different microbiota than wild-type animals (Lupp et al., 2007).”
A Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and the Complement Pathway (2011, background): “Enteric pathogens have also been shown to exert global changes on the gut microbiota in rodent models of inflammatory disease (Garrett et al., 2010; Lupp et al., 2007; Stecher et al., 2007).”
Mechanisms of inflammation-driven bacterial dysbiosis in the gut (2016, neutral): “In addition, oral infection with Citrobacter rodentium elicits robust inflammatory response and significantly reduced the microbial diversity of colonic microbiota while promoting the growth of facultative Enterobacteriaceae.(34) Several mechanisms have been proposed to account for blooms of Enterob”
Host remodeling of the gut microbiome and metabolic changes during pregnancy. (2012, background): “We suggest that a low-grade inflammation develops during pregnancy at the intestinal mucosal epithelium, and this inflammation may drive the microbial dysbiosis into a positive feedback loop with the altered host response (Lupp et al., 2007).”
NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. (2014, neutral): “Mice infected with C. rodentium or Salmonella enterica undergo massive changes in microbiota composition (Lupp et al., 2007; Stecher et al., 2007).”
Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism (2013, background): “Indeed, Enterobacteriaceae family members belonging to the genera Klebsiella (21), Citrobacter (22), and Salmonella (23, 24) can actively induce an inflammatory ienceTranslationalMedicine.org 10 July 2013 Vol 5 Issue 193 193ra91 1 microenvironment in the gastrointestinal tract that supports their pr”