Oxidant signals and oxidative stress.

By Toren Finkel. Current Opinion in Cell Biology, 2003

1,385 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3b1d25893fb91b5fba5e64390b8793bf6719ddef

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Citations in the corpus

Mitochondrial reactive oxygen species and cancer (2014, background): “The likelihood of cysteine oxidation of a given protein is a combination of solvent accessibility, local hydrogen peroxide concentration, and cysteine pKa [7].”
Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases (2020, background): “Superoxide radicals are produced by NADPH oxidases (NOX) and, to a minor extent, as by-products of a wide number of metabolic enzymes such as cyclooxygenase (COX) 1/2, lipoxygenase, xanthine oxidoreductase (XOR) and cytochrome p450 (Finkel, 2003).”
Cellular response to hyperosmotic stresses. (2007, background): “ROS convey signals from cytokines, hormones, and ions to downstream effectors, including transcription factors (87).”
Mechanisms of Cell Death in Oxidative Stress (2007, neutral): “Other RNS with potential biological reactivity include nitrogen dioxide (NO 2 ), nitroxyl (HNO), and nitrosonium cation (NO + ) (”
Redox redux: revisiting PTPs and the control of cell signaling. (2005, background): “H2O2 is a small, neutral molecule that is readily produced and removed following a physiological stimulus and can freely diffuse through cellular membranes; thus, it exhibits properties that are ideal for a regulator of signaling (Finkel, 2003).”
Oxidative status and telomere length in a long-lived bird facing a costly reproductive event (2011, background): “Oxidative stress triggers cell death viamembrane damage (cell necrosis) or by activating pro-apoptotic cellular pathways (Finkel 2003).”
Redox-based regulation of signal transduction: principles, pitfalls, and promises. (2008, background): “H2O2, a small and non-charged molecule that is readily produced and removed following these physiological stimuli, exhibits properties that are ideal for signal transduction [2].”
Reactive oxygen species in tumor progression. (2005, background): “Growing evidence suggests that in many instances, the production of reactive oxygen species is tightly regulated and their downstream targets are quite specific (7).”
Reconciling the chemistry and biology of reactive oxygen species. (2008, background): “Others have shown that many of the responses to growth factors, hormones and inflammatory cytokines involve redox signalin”
The Complex Regulation of Senescence (2012, background): “…either through damage (by reacting with DNA, proteins, lipids, etc.), or by acting as signaling molecules, e.g. in hormonal signaling or in response to biotic and abiotic factors (Finkel, 2003; Foyer and Noctor, 2005; Pitzschke et al., 2006; Møller et al., 2007) (see section V.B for nitric oxide).”