Mechanisms of Cell Death in Oxidative Stress

By S. Ryter, Hong-pyo Kim, A. Hoetzel, Jeong-Woong Park, K. Nakahira, Xue Wang, A. Choi. Antioxidants and Redox Signaling, 2007

1,283 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/035fb8d7fe4be5e048cef3d85bc07247f081d04c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. W. Ying
2. M. Wolin
3. M. Mbikay
4. Rahul D Pawar
5. Wasan Abdulmahdi
6. Brian B. Ratliff

In Molecular Biology

1. W. Ying
2. M. Wolin
3. Rahul D Pawar
4. Wasan Abdulmahdi
5. Brian B. Ratliff

Citations in the corpus

• Zinc Oxide Nanoparticles for Selective Destruction of Tumor Cells and Potential for Drug Delivery Applications (2010, background): “However, if ROS production exceeds the antioxidative defensive capacity of the cell, it results in oxidative damage of biomolecules, which can lead to cell death [40,41].”
• NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences (2008, positive): “Due to the critical roles of oxidative stress in cell death (247), it is expected that there would be an increasing number of studies indicating significant roles of NADPH in cell death.”
• Drug-Induced Oxidative Stress and Toxicity (2012, background): “It is well established that multiple kinase signaling pathways are affected by ROS ([48] for review) and kinase activation is critical in detecting oxidative stress and transducing signals to initiate a cellular response.”
• Oxidant Mechanisms in Renal Injury and Disease (2016, positive): “However, it is known that ROS and RNS promote apoptosis by directly activating caspase 3 and 8 ( via cysteine oxidization) (26) and inducing death receptor clustering on the plasma membrane (70, 261).”
• Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species (2012, background): “International Journal of Nanomedicine 2012:7 oxidative stress.(22,48,58) ROS typically include the superoxide radical (O2-), hydrogen peroxide (H 2 O 2 ), and hydroxyl radical (OH), which cause damage to cellular components including DNA and proteins.”
• REACTIVE OXYGEN SPECIES, CELLULAR REDOX SYSTEMS AND APOPTOSIS (2010, neutral): “Mitochondrial pathway—Stimulation of intrinsic mitochondrial apoptotic pathway by ROS and mitochondrial DNA damage promotes outer membrane permeabilization and mitochondria-to-cytosol translocation of cytochrome c, AIF, or Smac/Diablo that trigger caspase-dependent or caspase-independent cytosolic s”
• Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review (2012, background): “, on its ability to prevent excessive oxidation of its macromolecules, including DNA, proteins, and lipids (Ryter et al., 2007; Limon-Pacheco and Gonsebatt, 2009).”