IL-17, Produced by Lymphocytes and Neutrophils, Is Necessary for Lipopolysaccharide-Induced Airway Neutrophilia: IL-15 as a Possible Trigger

By S. Ferretti, O. Bonneau, G. Dubois, Carol E. Jones, A. Trifilieff. Journal of Immunology, 2003

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IL‐12 and IL‐23: master regulators of innate and adaptive immunity (2004, background): “IL-12 drives NK cell production of IFN-g, whereas recent data suggest that IL-23 drives IL-17 production by NK cells (unpublished observation) and neutrophils (87).”
Innate IL-17-producing cells: the sentinels of the immune system (2010, background): “The IL-17-mediated immune pathway is induced within hours following epithelial cell injury or activation of pattern recognition receptors (PRRs”
Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis (2011, neutral): “44 On 3 dpi, lungs were lavaged thrice with a total of 3 mL of PBS.”
The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines. (2010, neutral): “IL-17 is a pro-inflammatory cytokine that is produced predominantly by Th17 cells, but also by neutrophils (Ferretti et al., 2003; Kleinschnitz et al., 2006), cytotoxic T cells (Tzartos et al., 2008), as well as glial cells (Kawanokuchi et al., 2008; Tzartos et al., 2008) and plays a central role…”
IL-17-Mediated Regulation of Innate and Acquired Immune Response against Pulmonary Mycobacterium bovis Bacille Calmette-Guérin Infection1 (2007, background): “Recently, it was reported that neutrophils produce IL-17 in a model of LPS-induced lung inflammation (56); however, no IL-17 production by neutrophils was detected in our system.”