Organogenesis of lymphoid tissues

By R. Mebius. Nature reviews. Immunology, 2003

820 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/12a7f656acd70c4427454d9749c850294b9f62aa

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Citations in the corpus

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. (2008, background): “1 cell subset may be related to the previously described RORgt lymphoid tissue inducer (LTi) cells known to orchestrate development of programmed secondary and induced tertiary intestinal lymphoid aggregates (Eberl and Littman, 2004; Mebius, 2003).”
Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells (2009, background): “1668" language="eng" relation="no"> Lymph nodes optimize the efficiency of immunological responses by providing an environment that increases the chances that naive circulating lymphocytes will encounter their cognate antigen and, once this has occurred, by facilitating the activation and s”
Lymphangiogenesis: Molecular mechanisms and future promise. (2010, background): “express interleukin-7-receptor-α (IL-7Rα), CD45, and CD4 but lack CD3 (Drayton et al., 2006; Mebius, 2003).”
Lymphoid neogenesis in chronic inflammatory diseases (2006, background): “Also, the cellular and molecular basis of lymphoid organogenesis have been unveiled in recent years and this knowledge has been applied to the study of TLOs, showing remarkable similarity between the formation and structure of SLOs and TLO”
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling (2011, background): “Developing lymph nodes collect CD4 + CD3 − LTα + LT-β + cells that can differentiate into antigen-presenting cells or NK-like cells but not into T cells or B cell”
The noncanonical NF‐κB pathway (2012, background): “Secondary lymphoid organs are anatomical sites that provide a microenvironment for the maintenance and activation of lymphocytes and are thus important for the initiation of adaptive immune responses (93).”
Tertiary lymphoid structures in cancer (2022, background): “Furthermore, in patients with ovarian and uterine cancer, the presence of CXCL13+ CD103+ CD8+ T cells correlated with TLS abundance and with predicted neoantigen burden (83).”
Specific microbiota direct the differentiation of Th17 cells in the mucosa of the small intestine (2008, neutral): “In addition, at day 4 a significant proportion ( 25%) of lymphoid tissue inducer (LTi)-like CD4CD3 cells, found in cryptopatches and isolated lymphoid follicles in gut (Mebius, 2003), also expressed IL-17 (Figure S4B).”
NF-κB and the immune response (2006, background): “The initial events of lymphoid organogenesis involve the association of lymphotoxin (LT)a1b2-expressing hematopoietic cells and vascular cell adhesion molecule-1 (VCAM1)expressing stromal cells (for a review see Mebius, 2003).”