M. V. Vander Heiden
Molecular Biology · 2008–2018
A researcher in the Science corpus: 22 papers; trusts 65 researchers and is trusted by 58 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 592 citations into it; #536 of 17,773 by trust here, #423 by citations
- Cancer Research — 353 citations into it; #33 of 1,780 by trust here, #40 by citations
- Oncology — 132 citations into it
- Physiology — 76 citations into it
- Pulmonary and Respiratory Medicine — 65 citations into it
- Genetics — 59 citations into it
- Surgery — 56 citations into it; #939 of 1,106 by trust here, #287 by citations
- Cell Biology — 36 citations into it
Whom M. V. Vander Heiden trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
- Ralph J. Deberardinis
- V. Fantin
- Craig B. Thompson
- Lewis C. Cantley
- Javier A. Menéndez
- J. Engelman
- A. Le
- W. Kaelin
- S. Mazurek
- G. Semenza
Who trusts M. V. Vander Heiden overall
- Weiwei Yang
- Ralph J. Deberardinis
- J. Cantor
- James R. Broach
- C. V. Dang
- Andrew N. Lane
- Craig B. Thompson
- Sophia Y. Lunt
- D. Hanahan
- Jason W. Locasale
Papers from M. V. Vander Heiden's perspective
Ordered by how strongly the researchers M. V. Vander Heiden trusts endorse each paper. Same corpus, a different order for every researcher.
- Akt Stimulates Aerobic Glycolysis in Cancer Cells (Cancer Research)
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate (Nature)
- Why do cancers have high aerobic glycolysis? (Nature Reviews. Cancer)
- Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis (Proceedings of the National Academy of Sciences of the United States of America)
- ATP citrate lyase inhibition can suppress tumor cell growth. (Cancer Cell)
- Deregulation of Glucose Transporter 1 and Glycolytic Gene Expression by c-Myc* (Journal of Biological Chemistry)
- Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. (Journal of Clinical Investigation)
- c-Myc suppression of miR-23 enhances mitochondrial glutaminase and glutamine metabolism (Nature)
- HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. (Cell Metabolism)
- Activation of a metabolic gene regulatory network downstream of mTOR complex 1. (Molecules and Cells)
Their papers
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation (2009) — 15,359 citations
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth (2008) — 2,811 citations
- Activation of a metabolic gene regulatory network downstream of mTOR complex 1. (2010) — 1,964 citations
- Pyruvate kinase M2 is a phosphotyrosine-binding protein (2008) — 1,008 citations
- Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth (2009) — 782 citations
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia (2011) — 1,766 citations
- Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis (2012) — 990 citations
- Evidence for an alternative glycolytic pathway in rapidly proliferating cells (2010) — 645 citations
- Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. (2011) — 2,906 citations
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) — 5,732 citations
- Metabolic targets for cancer therapy (2013) — 641 citations
- Supporting aspartate biosynthesis is an essential function of respiration in proliferating cells (2015) — 1,066 citations
- Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer (2016) — 676 citations
- Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. (2015) — 754 citations
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis (2012) — 775 citations
- Targeting cancer metabolism: a therapeutic window opens (2011) — 1,380 citations
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate (2009) — 4,048 citations
- Understanding the intersections between metabolism and cancer biology (2017) — 1,919 citations
- Targeting Metabolism for Cancer Therapy (2017) — 787 citations
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages. (2015) — 600 citations