Michael S. Brown

Molecular Biology · Cell · 2000–2015

A researcher in the Science corpus: 13 papers; trusts 9 researchers and is trusted by 21 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 36 citations into it; #3,088 of 17,773 by trust here, #1,452 by citations
• Surgery — 33 citations into it; #49 of 1,106 by trust here, #31 by citations
• Oncology — 14 citations into it; #465 of 1,698 by trust here, #237 by citations
• Endocrine and Autonomic Systems — 8 citations into it

Whom Michael S. Brown trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. J. Goldstein
2. David M. Sabatini
3. Jay D. Horton
4. D. Cummings
5. Jonathan C. Cohen
6. J. Repa

Who trusts Michael S. Brown overall

1. J. Goldstein
2. J. Malhotra
3. Valeria Tosti
4. R. Kaufman
5. M. Laplante
6. Chunming Cheng
7. Peter Libby
8. Liangyou Rui

Papers from Michael S. Brown's perspective

Ordered by how strongly the researchers Michael S. Brown trusts endorse each paper. Same corpus, a different order for every researcher.

1. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
2. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. (Journal of Biological Chemistry)
3. TOR signaling in growth and metabolism. (Cell)
4. Role of LXRs in control of lipogenesis. (Genes & Development)
5. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. (Molecules and Cells)
6. The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. (Annual Review of Cell and Developmental Biology)
7. AKT/PKB signaling: navigating downstream. (Cell)
8. Oxysterols: modulators of cholesterol metabolism and other processes. (Physiological Reviews)
9. Wnt proteins are lipid-modified and can act as stem cell growth factors
10. Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes (Proceedings of the National Academy of Sciences of the United States of America)

Their papers

• Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes (2003) — 1,475 citations
• SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. (2002) — 5,004 citations
• ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. (2000) — 1,882 citations
• Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis (2010) — 733 citations
• Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1c* (2002) — 663 citations
• Protein sensors for membrane sterols. (2006) — 1,658 citations
• Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ (2000) — 1,589 citations
• A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins (2015) — 1,107 citations
• History of Discovery: The LDL Receptor (2009) — 1,213 citations
• Structure of N-terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol (2009) — 666 citations
• Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. (2008) — 1,178 citations
• Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. (2002) — 1,022 citations
• Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. (2000) — 857 citations