N. Hay
Molecular Biology · 2001–2016
A researcher in the Science corpus: 12 papers; trusts 25 researchers and is trusted by 34 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 204 citations into it; #1,224 of 17,773 by trust here, #1,476 by citations
- Cancer Research — 47 citations into it; #298 of 1,780 by trust here, #815 by citations
- Physiology — 44 citations into it; #1,366 of 2,276 by trust here, #1,555 by citations
- Cell Biology — 13 citations into it
- Cellular and Molecular Neuroscience — 8 citations into it
Whom N. Hay trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
- K. Inoki
- Julian Downward
- Dos D. Sarbassov
- G. Semenza
- E. Jacinto
- A. Gingras
- D. Fingar
- B. Manning
- Siraj M. Ali
- B. Raught
Who trusts N. Hay overall
- Y. Fouad
- A. Budanov
- C. Aanei
- Mauro Costa-Mattioli
- R. Shaw
- Jingxiang Huang
- David M. Sabatini
- M. Karin
- P. Vaupel
- L. Platanias
Papers from N. Hay's perspective
Ordered by how strongly the researchers N. Hay trusts endorse each paper. Same corpus, a different order for every researcher.
- TOR, a central controller of cell growth. (Cell)
- Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. (Genes & Development)
- Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR (Proceedings of the National Academy of Sciences of the United States of America)
- mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. (Cell)
- Regulation of cellular growth by the Drosophila target of rapamycin dTOR. (Genes & Development)
- Tsc tumour suppressor proteins antagonize amino-acid–TOR signalling (Nature Cell Biology)
- Regulation of translation initiation by FRAP/mTOR. (Genes & Development)
- TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling (Nature Cell Biology)
- The Mammalian Target of Rapamycin (mTOR) Partner, Raptor, Binds the mTOR Substrates p70 S6 Kinase and 4E-BP1 through Their TOR Signaling (TOS) Motif* (Journal of Biological Chemistry)
- Mammalian TOR: A Homeostatic ATP Sensor (Science)
Their papers
- Upstream and downstream of mTOR. (2004) — 4,365 citations
- Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. (2001) — 978 citations
- Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. (2003) — 881 citations
- Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. (2004) — 661 citations
- Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. (2001) — 1,011 citations
- The Akt-mTOR tango and its relevance to cancer. (2005) — 819 citations
- Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis (2008) — 771 citations
- AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress (2012) — 1,105 citations
- Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer (2013) — 818 citations
- Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? (2016) — 998 citations
- The pentose phosphate pathway and cancer (2014) — 1,299 citations
- The two TORCs and Akt. (2007) — 847 citations