B. Manning

Molecular Biology · Cell · 2002–2019

A researcher in the Science corpus: 17 papers; trusts 39 researchers and is trusted by 45 researchers here, as inferred from the citation graph.

Subfields

Molecular Biology — 392 citations into it; #670 of 17,773 by trust here, #627 by citations
Physiology — 97 citations into it; #106 of 2,276 by trust here, #176 by citations
Cell Biology — 62 citations into it; #1,967 of 2,073 by trust here, #1,182 by citations
Cancer Research — 55 citations into it; #542 of 1,780 by trust here, #385 by citations
Surgery — 38 citations into it
Genetics — 33 citations into it
Immunology — 29 citations into it; #944 of 2,160 by trust here, #1,518 by citations
Pharmacology — 11 citations into it

Whom B. Manning trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

Who trusts B. Manning overall

Papers from B. Manning's perspective

Ordered by how strongly the researchers B. Manning trusts endorse each paper. Same corpus, a different order for every researcher.

TSC2 mediates cellular energy response to control cell growth and survival. (Cell)
TOR signaling in growth and metabolism. (Cell)
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex (Science)
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling (Nature Cell Biology)
Akt regulates growth by directly phosphorylating Tsc2 (Nature Cell Biology)
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. (Genes & Development)
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. (Cell)
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. (Current Biology)
Upstream and downstream of mTOR. (Genes & Development)

Their papers

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. (2002) — 1,595 citations
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. (2003) — 1,260 citations
The LKB1 tumor suppressor negatively regulates mTOR signaling. (2004) — 1,144 citations
AKT/PKB signaling: navigating downstream. (2007) — 6,155 citations
Activation of a metabolic gene regulatory network downstream of mTOR complex 1. (2010) — 1,964 citations
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. (2004) — 1,421 citations
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling (2002) — 850 citations
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome (2014) — 771 citations
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output (2013) — 684 citations
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. (2008) — 1,242 citations
mTORC1 Induces Purine Synthesis Through Control of the Mitochondrial Tetrahydrofolate Cycle (2016) — 705 citations
A complex interplay between Akt, TSC2, and the two mTOR complexes (2009) — 767 citations
Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways (2011) — 637 citations
Targeting the PI3K-Akt pathway in human cancer: rationale and promise. (2003) — 1,414 citations
Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1 (2013) — 722 citations
AKT/PKB Signaling: Navigating the Network (2017) — 3,226 citations
The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism (2019) — 1,781 citations