Jason Moffat
Molecular Biology · 2004–2017
A researcher in the Science corpus: 9 papers; trusts 1 researcher and is trusted by 4 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 125 citations into it; #8,519 of 17,773 by trust here, #1,486 by citations
Whom Jason Moffat trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts Jason Moffat overall
Papers from Jason Moffat's perspective
Ordered by how strongly the researchers Jason Moffat trusts endorse each paper. Same corpus, a different order for every researcher.
- Functional siRNAs and miRNAs exhibit strand bias. (Cell)
- Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells (Nature)
- A large-scale RNAi screen in human cells identifies new components of the p53 pathway (Nature)
- A System for Stable Expression of Short Interfering RNAs in Mammalian Cells (Science)
- Systematic functional analysis of the Caenorhabditis elegans genome using RNAi (Nature)
- The Protein Kinase Complement of the Human Genome (Science)
- Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. (Cell)
- A resource for large-scale RNA-interference-based screens in mammals (Nature)
- Functional genomic analysis of C. elegans chromosome I by systematic RNA interference (Nature)
- mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. (Cell)
Their papers
- Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. (2006) — 1,535 citations
- A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. (2006) — 1,888 citations
- CellProfiler: image analysis software for identifying and quantifying cell phenotypes (2006) — 5,206 citations
- High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. (2015) — 1,489 citations
- Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning (2009) — 396 citations
- Exploration of essential gene functions via titratable promoter alleles. (2004) — 650 citations
- INHIBITION OF MITOCHONDRIAL TRANSLATION AS A THERAPEUTIC STRATEGY FOR HUMAN ACUTE MYELOID LEUKEMIA (2011) — 635 citations
- Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens (2017) — 521 citations
- Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens (2017) — 30 citations