NK cell recognition.

By L. Lanier. Annual Review of Immunology, 2005

3,037 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f8de0d7528318576c132ee58313dd982646add5d

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In Immunology

Citations in the corpus

Anti-immunology: evasion of the host immune system by bacterial and viral pathogens. (2006, background): “Among the various classes of leukocytes that can be regulated by viral proteins, particular attention has been paid recently to NK cells, T cells, dendritic cells, and macrophage (Ambagala et al., 2005; Andrews et al., 2005; Lodoen and Lanier, 2005; Pollara et al., 2005).”
NK cell development, homeostasis and function: parallels with CD8+ T cells (2011, background): “Interestingly, in both mice and humans, activated and memory CD8 + T cells also express inhibitory receptors for MHC class”
Self-tolerance of natural killer cells (2006, background): “Unlike T and B cells, the specificity of NK cells for target cells is not dominated by a single antigen receptor but, instead, is determined by a range of stimulatory and inhibitory receptors expressed at the surface of each NK cel”
T cell– and B cell–independent adaptive immunity mediated by natural killer cells (2006, background): “Mouse NK cells express variable combinations of Ly49 receptors, and the absolute number and relative frequency of NK cells expressing each Ly49 receptor combination depends on genetic backgroun”
Innate Lymphoid Cells: a new paradigm in immunology (2015, background): “In certain tissues, the prompt production of effector cytokines is shared with “innate” T cells, such as mucosa-associated invariant T (MAIT) cells that produce IFN-g, IL-17, and IL-22 (77); invariant NKT (iNKT) cells that produce IFN-g or IL-4 (78); and subsets of gd T cells that produce IFN-g and ”
Controlling NK Cell Responses: Integration of Signals for Activation and Inhibition (2013, background): “Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity.”
Cytokine-induced memory-like natural killer cells (2009, background): “Unlike adaptive T and B lymphocytes, NK cells do not somatically rearrange their receptor genes, but rely upon a finite number of germ line-encoded inhibitory and activating NK receptors capable of recognizing MHC class I and class I-like molecules (8, 9).”
Progressive loss of RORγt expression confers distinct functional fates to natural killer cell receptor-expressing RORγt+ innate lymphocytes (2010, positive): “1) allowing them to eliminate infected, transformed, or stressed cells (Lanier, 2005).”
Immunobiology of the TAM receptors (2008, background): “1, DX5 and CD69), which recognize ligands on target cell”
NK cells and cancer immunosurveillance (2008, background): “Altogether, it is now common sense that the activation of NK cells depends on an intricate balance between activating and inhibitory signals (Lanier, 2005): ‘healthy’ cells express NK-inhibiting MHC class I molecules and no or few activating NK ligands leaving NK cells quiescent.”
Activation, coactivation, and costimulation of resting human natural killer cells (2006, background): “In line with these findings and providing mechanistic insights, a recent study (71) showed that NKG2D–DAP10 recruitment of both a Grb2–Vav complex and the p85 subunit of PI3K is required for NKG2D-mediated cytotoxicity in IL-2-activated NK cells.”
Recognition of microorganisms and activation of the immune response (2007, background): “They express two types of receptor, activating and inhibitory, and these receptors recognize their cognate, host-encoded ligands on infected (target) cell”
Functions of natural killer cells (2008, background): “Activating NK cell receptors detect the presence of ligands on cells in 'distress', such as the stress-induced self ligands recognized by NKG2D (human ULBP and MIC molecules, as well as mouse RAE1, H60 and MULT1 molecules”