Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis.

By A. Chiricozzi, E. Guttman‐Yassky, M. Suárez‐Fariñas, K. Nograles, S. Tian, I. Cardinale, S. Chimenti, J. Krueger. Journal of Investigative Dermatology, 2011

687 citations recorded by the source corpus.

Subfields: Agronomy and Crop Science

View Paper: https://www.semanticscholar.org/paper/f2417de21c9f3c4d079321a5066e13c31f3c6b02

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Citations in the corpus

• The IL-17 family of cytokines in health and disease (2019, background): “One of the best-studied examples of synergy is with TNFα (Chiricozzi et al., 2011; Ruddy et al., 2004); consequently, bi-specific Abs are now in development for therapy (Fleischmann et al., 2017; Klunder et al., 2017; Kontermann and Brinkmann, 2015; Robert et al., 2017; Torres et al., 2016).”
• Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. (2012, neutral): “Infection or infestation 7 (26) 12 (43) 9 (30) 9 (31) 8 (29)”
• Immunology of Psoriasis (2014, background): “Furthermore, synergistic effects likely exist between IL-17 and TNF, given that a combination of the two cytokines induces greater changes in gene expression than either alone (89).”