Obesity, adiponectin and vascular inflammatory disease

By N. Ouchi, S. Kihara, T. Funahashi, Yuji Matsuzawa, K. Walsh. Current Opinion in Lipidology, 2003

761 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Epidemiology, Immunology

View Paper: https://www.semanticscholar.org/paper/de6c65e173f0198aa653f29b9d41756e8c7b4010

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. H. Fang
2. R. L. Judd
3. K. Walsh
4. N. Ouchi
5. Haiming Cao

In Epidemiology

1. H. Fang
2. R. L. Judd
3. K. Walsh
4. N. Ouchi
5. T. Funahashi
6. S. Kihara
7. Haiming Cao
8. Barry J. Goldstein

In Immunology

1. H. Fang
2. R. L. Judd

Citations in the corpus

• Adipokines in inflammation and metabolic disease (2011, background): “It is now well established that adipose tissue is not only involved in energy storage but also functions as an endocrine organ that secretes various bioactive substance”
• Adiponectin Regulation and Function (2018, positive): “A large number of rodent and human studies have demonstrated that adiponectin has anti-inflammatory properties in various disease states, including type 2 diabetes, nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease (84, 234, 254).”
• Dietary factors and low-grade inflammation in relation to overweight and obesity (2011, neutral): “Overexpression of adiponectin results in diminished size of the lesions observed following acute ischaemic myocardial infarction, increased angiogenic properties and reduced size of atheromatous plaques in the genetically predisposed apoE mouse((103)).”
• Adiponectin-mediated modulation of hypertrophic signals in the heart (2004, background): “The adipocytokine adiponectin is decreased in patients with obesity-linked disease”
• Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms (2005, background): “and are inversely correlated with cardiovascular risk factors including hyperlipidemia, blood pressure and C-reactive protein (CRP) level”
• Obesity, metabolic syndrome, and cardiovascular disease. (2004, neutral): “Adiponectin is one potentially important product (22).”
• Adiponectin: A novel adipokine linking adipocytes and vascular function. (2004, neutral): “As the visceral adipose mass is expanded, the secretion of many of these products is increased, including free fatty acids, TNF , ILs, resistin, leptin, and complement factors, which reduce insulin sensitivity and contribute to endothelial dysfunction (14).”
• Oxidative Stress in Obesity: A Critical Component in Human Diseases (2014, background): “The actions of leptin on cell functions are balanced by adiponectin [145], having antiproliferative and antiangiogenic effects [146].”