Adiponectin-mediated modulation of hypertrophic signals in the heart

By R. Shibata, N. Ouchi, Masahiro Ito, S. Kihara, I. Shiojima, D. Pimentel, M. Kumada, Kaori Sato, S. Schiekofer, K. Ohashi and 3 more. Nature Medicine, 2004

698 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms (2005, neutral): “and excessive cardiac remodeling after pressure overloa”
Cardiac remodeling in obesity. (2008, background): “Thus, whereas adiponectin may mediate a direct in vitro hypertrophic effect on primary cardiomyocytes (320), another study showed that both full-length and globular adiponectin attenuated endothelin (ET)-1-induced hypertrophy in cultured cardiomyocytes, suggesting a potential role in the pathogenesi”
Adipose tissue-derived factors: impact on health and disease. (2006, background): “cular injury (99, 138, 139); apolipoprotein E knockout mice”
Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets (2015, background): “Conversely, mice with depleted AMPK activity had an exacerbated degree of LV hypertrophy, adverse remodeling and dysfunction following cardiac injury (Shibata et al. 2004; Xu et al. 2014; Zarrinpashneh et al. 2008; Zhang et al. 2008).”