Adiponectin: A novel adipokine linking adipocytes and vascular function.

By Barry J. Goldstein, Rosario Scalia. Journal of Clinical Endocrinology and Metabolism, 2004

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How researchers see this paper

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Adiponectin Regulation and Function (2018, positive): “A number of studies have shown direct effects of adiponectin on endothelial and vascular smooth muscle cells (72, 85, 91).”
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. (2005, background): “Adiponectin Adiponectin is an adipocyte-secreted molecule that circulates in macromolecular complexes, increases fatty acid oxidation and glucose uptake, inhibits gluconeogenesis, and prevents atherosclerosis by direct effects on the vasculature (Goldstein and Scalia, 2004).”
Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. (2008, background): “Furthermore, adiponectin reduces vascular smooth muscle cell proliferation (VSMCs), migration and apoptosis by attenuating DNA synthesis inducing effects of growth factors including platelet-derived growth factor and fibroblast growth factor.(62) Increased levels of plasminogen activator inhibitor-1”