Casein micelle as a natural nano-capsular vehicle for nutraceuticals

By E. Semo, E. Kesselman, D. Danino, Y. Livney. 2007

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Structured biopolymer-based delivery systems for encapsulation, protection, and release of lipophilic compounds (2011, unknown): “It was recently shown that casein micelles, which are clusters of casein molecules (d1⁄4 100e300 nm), are capable of encapsulating and protecting non-polar molecules, such as hydrophobic nutraceuticals, vitamins and drugs (Portnaya et al., 2006; Semo et al., 2007; Shapira, Assaraf, & Livney, 2010).”
Bioavailability of nanoparticles in nutrient and nutraceutical delivery (2009, background): “In recent years, there is growing interest in using these reactive methods to transform globulin proteins and casein micelles in nanocapsules for the delivery of hydrophobic nutraceuticals and hydrophilic minerals [3,41].”
Overview of Microencapsulates for Use in Food Products or Processes and Methods to Make Them (2010, methodology): “Semo et al. (2007) used self assembled casein micelles as nanocapsular vehicle.”
Interactions between milk proteins and polyphenols: Binding mechanisms, related changes, and the future trends in the dairy industry (2018, background): “have been reported to have a potential to be used for development of novel transport systems for bioactive molecules.([21,22]) Based on this interest, the number of publications on milk protein–polyphenol interactions has risen sharply in the last decade.”