Synaptic organization of the mushroom body calyx in Drosophila melanogaster

By Kouji Yasuyama, Ian A. Meinertzhagen, F. Schürmann. 2002

281 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Neuroscience

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Citations in the corpus

An Integrated Micro- and Macroarchitectural Analysis of the Drosophila Brain by Computer-Assisted Serial Section Electron Microscopy (2010, background): “form the massive ‘‘microglomeruli = globular endings; [13,55]).”
Different classes of input and output neurons reveal new features in microglomeruli of the adult Drosophila mushroom body calyx (2012, methodology): “1B,C), mostly intrinsic neurons called Kenyon cells (KCs; Kenyon, 1896; Strausfeld et al., 2003) but also occasionally to other non-PN extrinsic neurons (ENs; Schürmann, 1987; Ito et al., 1998; Yasuyama et al., 2002; Tanaka et al., 2008).”
Olfactory representations by Drosophila mushroom body neurons. (2008, background): “Previous work suggests that the three classes play different roles in memory formation, possibly because they connect to different postsynaptic targets (Akalal et al. 2006; Krashes et al. 2007; Pascual and Preat 2001; Zars et al. 2000).”
Synaptic organization in the adult Drosophila mushroom body calyx (2009, methodology): “…have provided evidence that projection neuron boutons in the adult calyx are surrounded by a number of small postsynaptic profiles, including Kenyon cells and a few inhibitory interneurons, to form synaptic complexes called microglomeruli (Ganeshina and Menzel, 2001; Yasuyama et al., 2002).”
Synaptic connections of cholinergic antennal lobe relay neurons innervating the lateral horn neuropile in the brain of Drosophila melanogaster (2003, methodology): “The smaller ChAT boutons resemble those found in Drosophila mushroom body calyces (Yasuyama et al., 2002).”
Mushroom body efferent neurons responsible for aversive olfactory memory retrieval in Drosophila (2011, background): “We next examined immunoreactivity for choline acetyltransferase (ChAT) in the presynaptic terminals of MB-V2, as the antibody does not notably label cell bodie”
The GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning (2008, background): “These contacts were observed in the mushroom body calyx, an area of the brain that contains the mushroom body dendrites and presynaptic terminal”
Two pairs of mushroom body efferent neurons are required for appetitive long-term memory retrieval in Drosophila. (2013, background): “We first examined immunoreactivity for choline acetyltransferase (ChAT) in the presynaptic terminals of MB-V3 neurons because the antibody often does not label cell bodies of cholinergic neurons (Yasuyama et al., 2002).”
Patterns of growth, axonal extension and axonal arborization of neuronal lineages in the developing Drosophila brain. (2009, background): “Again, the calyx provides an example in this case: electron microscopic investigations have shown that well over two thirds of the postsynaptic terminal neurites belong to neurons of the MB lineages (Yasuyama et al., 2002).”
Evolution of insect mushroom bodies: old clues, new insights (2005, background): “The combined results of immunological and electron microscopical studies in Acheta, Apis andDrosophila reveal that microglomeruli are primarily composed of a cholinergic bouton from an afferent axon, surrounded by a number of f-actin containing Kenyon cell dendrites and GABAergic terminals (Ganeshin”
Are mushroom bodies cerebellum-like structures? (2011, background): “Many previous studies have drawn comparisons between the mushroom bodies and the cerebellum (Schürmann, 1987; Fahrenbach and Chamberlain, 1987; Li and Strausfeld, 1997; Laurent, 2002; Yasuyama et al., 2002; Frambach et al., 2004), but the present account will provide the first systematic comparison ”
Drosophila olfactory memory: single genes to complex neural circuits (2007, background): “, and beautiful anatomical work has described large glomerulus-like arrangements of cholinergic PN terminals in the adult mushroom body calyx intermingled with GABA-containing and occasional peptidergic and monoaminergic terminal”