Are mushroom bodies cerebellum-like structures?

By S. Farris. 2011

107 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Ecology, Evolution, Behavior and Systematics, Sensory Systems

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Gerald M. Rubin
2. Yoshinori Aso
3. Hiromu Tanimoto
4. Raphael Cohn
5. Ianessa Morantte
6. V. Ruta
7. P. Plaçais
8. T. Préat

In Ecology, Evolution, Behavior and Systematics

1. Yoshinori Aso
2. Gerald M. Rubin
3. Raphael Cohn
4. Ianessa Morantte
5. V. Ruta
6. R. Silver
7. N. A. Cayco-Gajic
8. Hiromu Tanimoto

In Sensory Systems

1. T. Préat
2. Yoshinori Aso
3. Hiromu Tanimoto
4. Gregory S. X. E. Jefferis
5. P. Plaçais
6. Gerald M. Rubin
7. V. Ruta
8. Raphael Cohn

Citations in the corpus

• Re-evaluating circuit mechanisms underlying pattern separation (2019, positive): “The role of the mushroom body in associative olfactory learning, and its broad similarities with the divergent circuitry of the cerebellar cortex (Farris, 2011), led to the idea that the mushroom body performs pattern separation (Laurent, 2002).”
• Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, background): “Moreover, long-term synaptic depression is known to occur in the granular cell synapses to Purkinje cells in the vertebrate cerebellum (Ito et al., 1982), a local neuronal circuit with many analogies to the MB (Schurmann, 1974; Laurent, 2002; Farris, 2011).”
• The neuronal architecture of the mushroom body provides a logic for associative learning (2014, background): “The MB may therefore represent an evolutionary primitive brain structure homologous in form and function to structures in the vertebrate brain (Schurmann, 1974; Laurent, 2002; Tomer et al., 2010; Farris, 2011).”
• Modelling learning and memory in Drosophila to understand Intellectual Disabilities. (2020, unknown): “For this reason, it is argued to be comparable to the mammalian hippocampus and cerebellum (Strausfeld and Hildebrand, 1999; Heisenberg, 2003; Campbell and Turner, 2010; Farris, 2011; Stevens, 2015).”
• A Complete Electron Microscopy Volume of the Brain of Adult Drosophila melanogaster (2017, background): “(PNs) provide the main sensory input to the MB; their connections with the MB intrinsic neurons, Kenyon cells (KCs), form a crucial stage of a fan-out fan-in network analogous to brain structures including the mammalian cerebellum (Farris, 2011; Stevens, 2015).”
• The complete connectome of a learning and memory centre in an insect brain (2017, background): “(2) There are multiple vesicles immediately adjacent to the T-bar or ribbon.”
• Distinct dopamine receptor pathways underlie the temporal sensitivity of associative learning (2019, background): “While the analogous circuit organization of the mushroom body and cerebellum has been well described (Farris, 2011), our observations suggest theymay share conservedmolecular mechanisms for temporally precise synaptic modulation.”