Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans
By Maria Grazia Roncarolo, S. Gregori, M. Battaglia, R. Bacchetta, K. Fleischhauer, M. Levings. Immunological Reviews, 2006
1,284 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/ad5fa0bc494f22bbcfe4e6bf281d22aa109884d1
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Immunology
- Shimon Sakaguchi
- Jacques Banchereau
- P. Krammer
- Angelika Schmidt
- Nina Oberle
- J. Bluestone
- Q. Tang
- A. Palucka
Citations in the corpus
- Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. (2008, background): “I Indeed, the earlier demonstration that addition of IL-10 of cocultures of monocyte-derived DCs allows the generation of CD4+ Treg cells is a step in this direction (Roncarolo et al., 2006; Stein- brink et al., 1999).”
- The Foxp3+ regulatory T cell: a jack of all trades, master of regulation (2008, background): “First, there are myriad subpopulations of T reg cells, including the CD4 + CD25 + Foxp3 + cells, interleukin 10 (IL-10)–producing 'Tr1' cell”
- Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis (2009, result): “Discussion The results from several studies have indicated that T cell–derived IL-10 is important for the prevention of coliti”
- The regulation of IL-10 production by immune cells (2010, background): “, but further evidence suggested that the production of IL-10 was associated with tolerant or regulatory T (T Reg ) cell response”
- Interleukin-35-mediated induction of a novel regulatory T cell population (2010, background): “There is substantial interest in the therapeutic potential of iT R cells because antigen-specific regulatory populations can be generated that are potently inhibitory in vivo”
- Rapamycin Promotes Expansion of Functional CD4+CD25+FOXP3+ Regulatory T Cells of Both Healthy Subjects and Type 1 Diabetic Patients1 (2006, result): “It is therefore unclear whether the adaptive Tregs described in these studies are similar to the in vitro induced Tregs (27) or Treg type 1 cells, which up-regulate CD25 and FOXP3 upon in vitro activation (28).”
- SOCS proteins, cytokine signalling and immune regulation (2007, background): “There is another type of regulatory T cell (T regulatory 1 (T R 1) cells) that expresses high levels of IL-10 but does not express FOXP3 (Ref”
- TH1 cells control themselves by producing interleukin-10 (2007, neutral): “and antigen-driven regulatory CD4 + T cells&hairsp”
- The tumor microenvironment and its role in promoting tumor growth (2008, background): “Oncogene proliferation and suppress anti-tumor responses of both CD4þCD25 and CD8þCD25 T cells using distinct molecular pathways (Roncarolo et al., 2006; Bacchetta et al., 2007).”