Hematopoietic stem cells: the paradigmatic tissue-specific stem cell.

By David Bryder, Derrick J. Rossi, Irving L. Weissman. American Journal of Pathology, 2006

770 citations recorded by the source corpus.

Subfields: Genetics, Hematology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a90fc953199bbed1092645856c95d87c33a1a5fe

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Citations in the corpus

Hematopoietic stem-cell transplantation. (2006, background): “Hematopoietic stem cells (HSCs) are characterized by the ability to self-renew and differentiate into all mature blood lineages.(1,2) Hematopoiesis is a continuous developmental process in which HSCs make specific cell fate decisions, producing the various blood lineages.”
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age (2011, background): “H is initiated by hematopoietic stem cells (HSC) that can self-renew and progressively differentiate into a hierarchy of committed progenitors that ultimately give rise to mature blood cells (1).”
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. (2007, background): “Hematopoiesis proceeds through an organized developmental hierarchy initiated by hematopoietic stem cells (HSC) that give rise to progressively more committed progenitors and eventually terminally differentiated blood cells (Bryder et al., 2006).”
Identification of white adipocyte progenitor cells in vivo. (2008, background): “…proliferation and differentiation in hematopoietic, epithelial, and spermatogonial stem cells previously used in analogous cell transplant studies (Bryder et al., 2006; Fata et al., 2001; Thayer et al., 2001), WAT in adult rodents displays only low levels of cell proliferation and new adipocyte…”
Long-term propagation of distinct hematopoietic differentiation programs in vivo. (2007, methodology): “The persistence of such a significant contribution to myelopoiesis by these CD45midlin Rho SP cells clearly distinguishes them functionally from STRCs, which have been defined in the literature by an inability to produce detectable GM progeny beyond 6–12 weeks (Morrison and Weissman, 1994; Adolfsson”
SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors (2013, background): “A number of markers permit the prospective identification and isolation of hematopoietic stemcells (HSCs) andmultipotent progenitors (MPPs) (Bryder et al., 2006).”
Extracting a Cellular Hierarchy from High-dimensional Cytometry Data with SPADE (2011, neutral): “In this hierarchy, multipotent self-renewing stem and progenitor cells give rise to all of the terminally differentiated cell types.”
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. (2007, background): “Hematopoiesis represents a prototype system for the study of selection, establishment, and restriction of individual developmental programs from one common precursor (Bryder et al., 2006).”
Stems cells and the pathways to aging and cancer. (2008, background): “…exemplified in the hematopoietic system (see the Review by S.H. Orkin and L.I. Zon, page 631 of this issue), the existence of hierarchical relationships between stem and progenitor cells is emerging as a common feature of other tissue-specific stem cell compartments as well (Bryder et al., 2006).”