The importance of the ratio of omega-6/omega-3 essential fatty acids.

By A. Simopoulos. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2002

3,973 citations recorded by the source corpus.

Subfields: Genetics, Nutrition and Dietetics, Physiology

View Paper: https://www.semanticscholar.org/paper/a56c91d7aad8f84000f98bccae770481bab2a4e7

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Citations in the corpus

So depression is an inflammatory disease, but where does the inflammation come from? (2013, positive): “commonly used in the production of processed foods, increases the production of pr -inflammatory cytokines [67].”
Spirulina as a functional ingredient in broiler chicken diets (2016, background): “These fatty acids are not consumed in adequate amounts in modern Western societies (Simopoulos, 2008), and it has been reported that their consumption could benefit foetus growth and protect from numerous chronic diseases, that is, infections, cancer, asthma, depression, heart and autoimmune disease”
Nutritional Value of Fish: Lipids, Proteins, Vitamins, and Minerals (2018, background): “An intake ratio of 1 to 4 is generally recommended (Simopoulos, 2001, 2002b).”
Hempseed as a nutritional resource: An overview (2004, background): “…the utility of EFAs and other PUFAs in healing and immune response (Manku et al., 1982, 1984; Bordoni et al., 1988; Oliwiecki et al., 1991; Sakai et al., 1994; Yu & Björkstén, 1998; Derek & Meckling-Gill, 1999; Harbige et al., 2000; Harbige & Fisher, 2001; Horrobin, 2000; Simopoulos, 2002a,b).”
Fatty acid composition of several wild microalgae and cyanobacteria, with a focus on eicosapentaenoic, docosahexaenoic and α-linolenic acids for eventual dietary uses (2011, background): “On theother hand, studies have shown that a balanced ratio of ω6/ω3 in one's diet decreases the doses of pharmaceutical medications required; a decrease in ω6 intake, concomitantwith an increase inω3 intake is accordingly recommended to assure homeostasis and regular health (Simopoulos, 2002).”
Biochemical characterization of microalgal biomass from freshwater species isolated in Alberta, Canada for animal feed applications (2015, background): “Although dietary fatty acid requirements and optimum n−3:n−6 ratios vary between farmed animal species; generally diets that fall below a ratio of 1:1 have been implicated with disease pathogenesis such as cardiovascular disease, cancer and impaired immune function while higher ratios promote an ant”
EVALUATION OF FATTY ACIDS PROFILE AND THE CONTENT OF SOME SECONDARY METABOLITES IN SEEDS OF DIFFERENT FLAX CULTIVARS (LINUM USITATISSIMUM L.) (2007, background): “Recently there has been a growing interest in the probiotic properties of flax and in its beneficial effects on coronary heart disease, some kinds of cancer and neurological and hormonal disorders (Huang and Milles, 1996; Huang and Ziboh, 2001; Simopoulos, 2002).”
Influence of feed supplementation with Cannabis sativa on quality of broilers carcass. (2010, background): “The oil of Cannabis sativa contains 75-80% polyunsaturated fatty acids and is the most perfectly balanced oil due to the presence of omega 3 and omega 6 fatty acids which are essential for good health and growth (Erasmus, 1999; Simopoulos, 2002).”
Marine and farmed fish in the Polish market: Comparison of the nutritional value (2011, background): “As mentioned in the introduction, according to several scientists (Kolanowski, 2000; Leskanich & Noble, 1997; Simopoulos, 2002), the prophylactic activity of fatty acids is also a function of the n 3 to n 6 acid ratio.”