Neuronal specification in the spinal cord: inductive signals and transcriptional codes

By T. Jessell. Nature reviews genetics, 2000

2,154 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9d288051e77030940ddb0dc694ae6dfed51982de

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Citations in the corpus

The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. (2001, methodology): “Expression of the Olig genes persists and Jessell, 1996; Jessell, 2000).”
Neuronal subtype specification in the cerebral cortex (2007, background): “How are these various projection neuron subtypes generated during corticogenesis? Insights from years of study in the spinal cord and retina provide models for how a diversity of neuronal types can be generate”
Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2. (2001, background): “…show that Olig2 has a critical role in cord, whether destined to supply somatic or visceralintegrating diverse features of motor neuron differentitargets, arise from a common and apparently uniformation in the developing spinal cord. set of progenitor cells within the pMN domain (Jessell, 2000).”
Hedgehog: functions and mechanisms. (2008, background): “The effect of Hh dose on target tissue responses is best characterized in the specification of cell identities in the ventral neural tube (Jessell 2000; Patten and Placzek 2000; Marti and Bovolenta 2002).”
Directed differentiation of embryonic stem cells into motor neurons. (2002, background): “The specification of MN fate in vivo can be considered in three sequential steps: (1) the primary neuralization of ectodermal cells, (2) the secondary caudalization of neural cells, and (3) the ventralization of caudalized neural cells (Jessell, 2000; Wilson and Edlund, 2001).”
Locomotor circuits in the mammalian spinal cord. (2006, methodology): “Adapted from Jessell (2000) and Goulding & Pfaff (2005).”
The Sox9 transcription factor determines glial fate choice in the developing spinal cord. (2003, background): “4a–j), indicating that at least the three ventralmost domains of the ventricular zone (Jessell 2000) kept their identity and position along the dorsoventral axis.”
Molecular mechanisms of axon guidance. (2006, background): “On the other side of the spinal cord, bone morphogenetic proteins (BMPs) pattern dorsal neurones (Jessell, 2000).”
Morphogen gradient interpretation (2001, background): “Ptc absorbs Hh and Sonic hedgehog (Shh) near their source, thereby making their supply limiting further awa”
Area patterning of the mammalian cortex. (2007, background): “Similar mechanisms appear to operate in the developing vertebrate brain, for example during the differentiation of rhombomeres in the hindbrain (Kiecker and Lumsden, 2005) and establishment of unique progenitor domains in the ventral spinal cord (Jessell, 2000; Shirasaki and Pfaff, 2002).”
The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. (2003, positive): “…of this chemoattractant(s) has, however,chemoattractant for commissural axons and show remained elusive.that a morphogen can also act as an axonal chemoatIn addition to regulating axon guidance, the floor platetractant. is also known for its role in morphogen secretion (reviewed in Jessell, 2000).”
Promoter Choice Determines Splice Site Selection in Protocadherin α and γ Pre-mRNA Splicing (2002, background): “Interestingly, each Pcdh V exon contains ties (Jessell, 2000).”
Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons. (2004, background): “Similarly, it is unclear how transient changes in shape might affect subsequent development of the neural tube, where spatial relationships are important in the specification of spinal cord cell types (reviewed by Jessell, 2000 ).”