Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons.

By J. Incardona, T. Collier, N. Scholz. Toxicology and Applied Pharmacology, 2004

828 citations recorded by the source corpus.

Subfields: Aquatic Science, Health, Toxicology and Mutagenesis, Oceanography

View Paper: https://www.semanticscholar.org/paper/f171b2ec0092b995f1cc90021165c4de5f79a073

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Aquatic Science

1. A. Farrell
2. J. Meador

In Health, Toxicology and Mutagenesis

1. A. Farrell
2. J. Meador

Citations in the corpus

• Ion homeostasis and interrenal stress responses in juvenile Pacific herring, Clupea pallasi, exposed to the water-soluble fraction of crude oil (2005, background): “Recently, work on the potential mechanisms underlying the common suite of PAH-induced developmental abnormalities in fish have been undertaken ( Incardona et al., 2004 ).”
• Perspective on Ecotoxicology of PAHs to Fish (2007, background): “Fish embryos exposed to petrogenic PAH mixtures (Incardona et al. 2004)”
• Prevalence of External Skin Lesions and Polycyclic Aromatic Hydrocarbon Concentrations in Gulf of Mexico Fishes, Post-Deepwater Horizon (2014, result): “However, the PAH composition of erosional sources in coastal Louisiana (Iqbal et al. 2007) differs substantially from that of the Deepwater Horizon oil (Reddy et al. 2012) and our profiles (Figures 5, 6). Iqbal et al. (2007) found a very low ratio of parent to C4 NHP (»1:10), which is characteristic”
• Rationale and Procedures for Using the Tissue-Residue Approach for Toxicity Assessment and Determination of Tissue, Water, and Sediment Quality Guidelines for Aquatic Organisms (2006, background): “Even though all PAH congeners may be considered additive for the narcosis mode of action (Di Toro et al. 2000), the biological responses for PAHs are quite varied (Payne et al. 2003; Barron et al. 2004a; Incardona et al. 2004).”
• Zebrafish as a model vertebrate for investigating chemical toxicity. (2005, background): “In fact, the majority of studies with MO assays have been carried out in the zebrafish, and together with the vast catalog of mutant zebrafish, have proven invaluable for the functional definition of genes required for normal development.”
• Does the Alberta Tar Sands Industry Pollute? The Scientific Evidence (2009, background): “Fish embryos exposed to complex mixtures of petrogenic PAHs display a characteristic suite of abnormalities that include cardiac dysfunction, edema, spinal curvature, and reduction in the size of the jaw and other craniofacial structures [82].”