Neuronal subtype specification in the cerebral cortex

By B. Molyneaux, P. Arlotta, J. Menezes, J. D. Macklis. Nature Reviews Neuroscience, 2007

1,626 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/2f9902940edf4938a3bbf4c63840e33586f2f432

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Citations in the corpus

Area patterning of the mammalian cortex. (2007, background): “The VZ generates deeper-layer neurons, including subplate (SP) and layer 6 and layer 5 projection neurons; the SVZ is a prominent source of superficial-layer neurons (Kriegstein and Noctor, 2004; Molyneaux et al., 2007).”
Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. (2008, background): “During late corticogenesis, the late/upper CP neurons and their progenitors, occupying the VZ/SVZ during mid-late gestation, express Brn2 (Figure S5B; Hevner et al., 2003a; Frantz and McConnell, 1996; Molyneaux et al., 2007 ).”
The maternal interleukin-17a pathway in mice promotes autismlike phenotypes in offspring (2016, background): “5 as well as in the adult brain using antibodies specific for proteins expressed in the cortex in a layer-specific manner (25): Special AT-rich sequencebinding protein 2 (SATB2) (26), T-brain-1 (TBR1) (27), and chicken ovalbumin upstream promoter transcription factor-interacting protein 2 (CTIP2) (2”
Adult Mouse Cortical Cell Taxonomy by Single Cell Transcriptomics (2016, positive): “7, 35, 36), and were primarily derived from the Ntsr1-Cre line (Fig 2b), while the other two (L6a-Syt17 and L6a-Car12) do not express Foxp2, and were isolated as tdT − cells from L6 of the same Cre line.”
The Cellular and Molecular Landscapes of the Developing Human Central Nervous System (2016, positive): “Newly born projection neurons migrate to their final laminar position in the emerging CP in a precise inside-first, outsidelast gradient (Bystron et al., 2008; Leone et al., 2008; Marín-Padilla , 2014; Meyer, 2007; Molyneaux et al., 2007; Shibata et al., 2015).”
Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain (2015, background): “Neocortical pyramidal neurons provide the long-range excitatory output of the brain, and inhibitory neurons modulate the rate and temporal structure of this network output (Molyneaux et al., 2007; Rudy et al., 2011).”
Brain organoids: advances, applications and challenges (2019, background): “Furthermore, unlike in the perinatal neocortex, the cortical layers in organoids cannot be discriminated based on their neuron distribution and density, partially owing to them exhibiting drastically fewer layers of CP neurons (Molyneaux et al., 2007).”
Systematic analysis of neural projections reveals clonal composition of the Drosophila brain. (2013, positive): “jp a neural stem cell divides asymmetrically to give birth to a family of clonally associated neurons [2, 3].”
Satb2 regulates callosal projection neuron identity in the developing cerebral cortex. (2008, positive): “…can be classified broadly as either corticocortical neurons, which extend axons within the telencephalon to ipsilateral or contralateral targets, or subcortical projection neurons, whose targets include the thalamus, midbrain, hindbrain, and spinal cord (McConnell, 1995; Molyneaux et al., 2007).”
A Mammalian enhancer trap resource for discovering and manipulating neuronal cell types (2016, methodology): “We also examined the expression of previously identified layer 6 marker genes (Molyneaux et al., 2007; Zeisel et al., 2015) and of genes used to generate BAC-Cre lines having layer 6 expression (Harris et al., 2014).”
Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell–derived neocortex (2013, background): “T mammalian neocortex has a multilayered structure (layers I–VI) (1).”
Principal Differences Analysis: Interpretable Characterization of Differences between Distributions (2015, background): “[44] Molyneaux BJ, Arlotta P, Menezes JRL, Macklis JD (2007) Neuronal subtype specification in the cerebral cortex.”