The ATP synthase is involved in generating mitochondrial cristae morphology

By P. Paumard, J. Vaillier, B. Coulary, J. Schaeffer, Vincent Soubannier, D. Mueller, D. Brèthes, J. di Rago, J. Velours. EMBO Journal, 2002

794 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9cbfc43bdfa6a02e2023d2d25fd7dc1cf8dee68c

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Citations in the corpus

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity (2003, background): “, and mutations in the electron-transport complex V ATP synthase affect mitochondria cristae formatio”
Dimer ribbons of ATP synthase shape the inner mitochondrial membrane (2008, background): “Deletion of subunits e or g resulted in abnormal mitochondria with layered onion-like inner membranes instead of cristae (Paumard et al, 2002).”
Mitochondria: In Sickness and in Health (2012, background): “In addition, the regulated dimerization/ oligomerization of ATP synthase is a major driving force for inner-membrane structure, possibly inducing and/or stabilizing the curvature of crista membranes (Paumard et al., 2002; Strauss et al., 2008).”
Dynamics of mitochondrial morphology in healthy cells and during apoptosis (2003, background): “Another mediator of mitochondrial fusion, the large dyna- min-like GTPase, Mgm1, may participate in the fusion and remodeling of the IMM.”
Functions and dysfunctions of mitochondrial dynamics (2007, background): “Mitochondrial F 1 F 0 ATP synthase , a rotary enzyme embedded in the inner membrane that couples proton pumping to ATP synthesis, is essential for normal cristae structur”
Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency (2013, background): “Interestingly, cristae shape and ATPase dimers are linked: in yeast mutants where the ATPase cannot dimerize, cristae are disorganized (Paumard et al., 2002; Minauro-Sanmiguel et al., 2005; Strauss et al., 2008), whereas in mammalian cells, increased cristae density favors ATPase dimerization during”
Mitochondrial ATP synthase: architecture, function and pathology (2011, background): “It has been shown in yeast that in the absence of complex V dimerization (by depleting subunits e and g) normal cristae formation is hampered, resulting in onionlike structures (Paumard et al. 2002).”
Mitochondrial Cristae: Where Beauty Meets Functionality. (2016, background): “Deletion of subunits e and g of ATP synthase in yeast and in human cell lines abolished the dimerization of ATP synthase and caused changes to the cristae membrane [64,65].”