The role of oxidative stress in the pathogenesis of age-related macular degeneration.

By S. Beatty, H. Koh, M. Phil, D. Henson, M. Boulton. Survey of ophthalmology, 2000

2,041 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/9a7359082243838fd5b806e24d53ec3412039ce8

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Citations in the corpus

The Impact of Oxidative Stress and Inflammation on RPE Degeneration in Non-neovascular AMD (2017, result): “…M anuscript A uthor M anuscript A uthor M anuscript the work of Ham et al in 1978 (Ham et al., 1978), photo-oxidative stress has been linked with oxidative damage to the retina, RPE, and choroid, and multiple other works have substantiated this observation, as reviewed in (Beatty et al., 2000).”
Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. (2003, neutral): “9) 833 (33) 214 (27) Overweight (25–29.”
The retinal pigment epithelium in visual function. (2005, background): “Thus, during each day, the concentration of light-induced toxic substances increases inside the photoreceptors (45).”
Oxidative Stress, Prooxidants, and Antioxidants: The Interplay (2014, background): “(1) Macular degeneration Eyes Reactive oxygen intermediates (ROI) [206]”
Current concepts in the pathogenesis of age-related macular degeneration. (2004, background): “Major antioxidants in the retina and RPE include water-soluble metabolites and enzymes (vitamin C [ascorbic acid], glutathione, catalase, glutathione peroxidase, and superoxide dismutase), lipidsoluble substances (vitamin E [ -tocopherol], retinoids [vitamin A derivatives], and carotenoids), and mel”
Potential Role of Carotenoids as Antioxidants in Human Health and Disease (2014, background): “Moreover, they are well-known for excellent ROS scavenging properties [77], which are of special significance, also due to the fact that biochemical processes that occur within photoreceptors (phototransduction and oxidative phosphorylation) are essential sources of ROS [161].”
Free Radicals, Antioxidants in Disease and Health (2008, background): “Even if antioxidant supplementation is receiving enthusiastic debate and is increasingly adopted in many industrial countries, supporting evidence is still ambiguous (5-59).”
Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides (2006, background): “These ROIs, including hydrogen peroxide, hypochlorite ions, hydroxyl radicals, hydroxyl ions and superoxide anion”
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. (2005, background): “Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina, G J Anderson 1, W E Connor, J D Corliss, 1990 Jan;27(1):89-97. doi: 10.1203/00006450- 199001000-00023. https://pubmed.ncbi.nlm.nih.gov/2136947/ Essential fatty acids, DHA and human brain, Meharb”
Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. (2003, background): “Additional supporting observations are those of Richter and his associates that a lipofuscin component,N-retinyl-Nretinylidene ethanolamine (A2E), induces apoptosis in RPE cells, thus inducing AMD (141).”
Melatonin as a natural ally against oxidative stress: a physicochemical examination (2011, background): “In addition, oxidative stress has been associated with ocular [61, 62], renal [33, 63], and pulmonary [64–67] diseases; rheumatoid arthritis [68], fetal growth restriction, and pre-eclampsia in prenatal medicine [69–73].”