Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides

By Junping Chen, S. Patil, S. Seal, J. McGinnis. Nature Nanotechnology, 2006

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Acute toxicity of cerium oxide, titanium oxide and iron oxide nanoparticles using standardized tests (2011, methodology): “Accordingly, CeO2 is being used as an antioxidant to block the enzymatic activity that ca uses glaucoma [10] and other retinal disorders [11].”
Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties (2008, neutral): “This could be particularly relevant to cerium oxide.(30) 32”
Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. (2007, background): “Other potential biological uses of nanoceria have emerged from studies showing protection of primary cells from the detrimental effects of radiation therapy [10], prevention of retinal degeneration induced by intracellular peroxides [11] and neuroprotection to spinal cord neurons [12].”
Direct and indirect CeO2 nanoparticles toxicity for Escherichia coli and Synechocystis (2009, result): “However, they led to contrasted conclusions even when the studied biological targets were similar (Tarnuzzer et al. 2005; Auffan et al. 2006; Chen et al. 2006).”