Decision-making processes following damage to the prefrontal cortex.

By Facundo Manes, Barbara J. Sahakian, Luke Clark, Robert D. Rogers, N. Antoun, Michael R. F. Aitken, Trevor W. Robbins. Brain : a journal of neurology, 2002

821 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/8dc612d4cd8afa3978142b19d10b001201b10271

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

1. Antoine Bechara
2. E. T. Rolls
3. Trevor W. Robbins
4. Gregory J. Quirk
5. Martha J. Farah
6. John P. O'Doherty
7. Lesley K. Fellows
8. Mohammed R. Milad

Citations in the corpus

• The Iowa Gambling Task and the somatic marker hypothesis: some questions and answers. (2005, background): “Fellows and Farah [14], and Manes and colleagues [ 22 ], have demonstrated this, as have we [23,24].”
• Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task (2003, result): “While this was not an a priori region of interest (Manes et al., 2002) showed that patients with discreet lesions to the MPFC were selectively impaired on the Iowa Gambling Task when compared to two other decision-making tasks.”
• Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making (2008, background): “This dissociation between the effects of vmPFC and dorsal PFC damage replicates our earlier observations with the Cambridge Gamble Task (Rahman et al., 1999; Mavaddat et al., 2000; Manes et al., 2002), although in these earlier studies the pathology was less focal.”
• Fear extinction in rats: implications for human brain imaging and anxiety disorders. (2006, background): “The role of the human vmPFC in the inhibition of inappropriate emotional responses is well documented in the literature (Bechara et al., 1999; Manes et al., 2002; Clark et al., 2003).”
• Functions of the Frontal Lobes: Relation to Executive Functions (2011, background): “The tasks are complex and await identification of the fundamental processes, some perhaps ‘‘executive’’ (Manes et al., 2002).”
• Reward-related Reversal Learning after Surgical Excisions in Orbito-frontal or Dorsolateral Prefrontal Cortex in Humans (2004, background): “A similar argument is made by Manes et al. (2002) who showed how the ventral and dorsal aspects of the prefrontal cortex must interact in the maintenance of rational and ‘‘nonrisky’’ decision-making tasks.”
• The roles of orbital frontal cortex in the modulation of antisocial behavior. (2004, background): “, 1999); though, for data challenging the role of orbital frontal cortex, per se, in these tasks, see (Manes et al., 2002).”
• Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. (2004, background): “In agreement with recent reports (Manes et al., 2002; Clark et al., 2003), but in contrast to those of Bechara et al. (1998), we found that unilateral DLF damage led to impaired IGT performance of a similar magnitude to the effect of VMF damage.”
• Assessment of Hot and Cool Executive Function in Young Children: Age-Related Changes and Individual Differences (2005, background): “…disadvantageous decks, patients with damage to VM–PFC continue to choose from these disadvantageous decks (e.g., Bechara et al., 1994; Bechara, Tranel, & Damasio, 2000; Bechara, Tranel, Damasio, & Damasio, 1996; but see Manes et al., 2002, for some qualifications regarding lesion focus and extent).”
• Behavioral models of impulsivity in relation to ADHD: Translation between clinical and preclinical studies (2006, neutral): “These patients persist in making risky choices on the Iowa gambling task (Bechara, Damasio, Damasio, & Anderson, 1994; Bechara, Damasio, Damasio, & Lee, 1999) and increased betting in the presence of normal probability judgements (Manes et al., 2002).”
• Neural substrates of faulty decision-making in abstinent marijuana users (2005, background): “Since performance of this task relies on the integrity of the right OFCmore than the left OFC (Bechara et al., 2000b; Manes et al., 2002; Tranel et al., 2002), deficits in right OFCwould logically result in poor task performance.”