Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans.

By Lesley K. Fellows, Martha J. Farah. Cerebral Cortex, 2004

651 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, General Decision Sciences

View Paper: https://www.semanticscholar.org/paper/6c9a602ff25aebfee239b65bb32ea2d424b77d2e

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Citations in the corpus

Functional imaging studies of emotion regulation: A synthetic review and evolving model of the cognitive control of emotion (2012, neutral): “In the present model, phenomena like extinction (or stimulus-reward reversal learning, which also depends upon vmPFC 148, 149 ), are somewhat hybrid phenomena.”
Evidence for Segregated and Integrative Connectivity Patterns in the Human Basal Ganglia (2008, background): “…such as OFC and MPFC, are involved in processing different aspects of motivational context information for decision-making (Elliott and Carson, 2000; Elliott et al., 2000; Fellows and Farah, 2005a,b), whereas DLPFC is important for cognitive contextual representation (Elliott et al., 2000).”
Decision-making Competence, Executive Functioning, and General Cognitive Abilities (2012, background): “Moreover, ventromedial patients may show poor IGT performance because of impairments in reversal learning: difficulties in learning that an option that initially seemed “good” has turned “bad” (e.g. Fellows & Farah, 2005; Maia & McClelland, 2005).”
The cognitive control of emotion. (2005, background): “On the control side, findings of activation in ventral lateral and medial PFC, OFC and/or ACC have been observed consistently, supported by neuropsychological studies showing impairments of reversal learning in patients with lesions of ventral and orbital but not dorsolateral PFC [ 64 ,65] .O n the ”
Reward-Related Cortical Inputs Define a Large Striatal Region in Primates That Interface with Associative Cortical Connections, Providing a Substrate for Incentive-Based Learning (2006, background): “…prefrontal cortex into the dorsal anterior cingulate cortex (dACC), the ventral , medial prefrontal cortex (vmPFC), OFC, and DLPFC based on specific roles for mediating different aspects of error prediction and decision making (Elliott et al., 2000a,b; Walton et al., 2004; Fellows and Farah, 2005).”
Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making (2008, background): “Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making”
Meeting of minds: the medial frontal cortex and social cognition (2006, background): “Studies of patients with lesions to the oMFC support this characterization of the role of this regio”
Emotion and Rationality: A Critical Review and Interpretation of Empirical Evidence (2007, background): “Findings by Fellows and Farah (2005) suggest that the poor performance of VMPC patients in the”
The orbitofrontal cortex and beyond: from affect to decision-making. (2008, background): “…are social reinforcers) (Hornak et al., 1996, 2003; Rolls, 1999b), in reversing stimulusreward associations (Berlin et al., 2004; Fellows, 2007; Fellows and Farah, 2003, 2005; Hornak et al., 2004; Rolls et al., 1994), and in emotional behaviour and subjective emotional states (Hornak et al.,…”
The neural architecture of emotion regulation (2007, result): “Consistent with these findings, neuropsychological studies have shown impairments of stimulus-reinforcer reversal learning in patients with lesions of ventral and orbital but not dorsolateral PFC (Fellows & Farah, 2003, 2004; Hornak et al., 2004).”
Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior (2010, positive): “Indeed, the IGT may present reversal-learning features (Dunn et al., 2006) and reversal learning impairments have been found to explain IGT deficits in patients with lesions to the left lateral OFC (Fellows and Farah, 2005).”
The Iowa Gambling Task and the somatic marker hypothesis: some questions and answers. (2005, background): “Fellows and Farah [ 14 ], and Manes and colleagues [22], have demonstrated this, as have we [23,24].”
The Presence of an Attractive Woman Elevates Testosterone and Physical Risk Taking in Young Men (2010, background): “One task that has been shown in fMRI studies to target the VMPFC is a ‘‘reversallearning’’ procedure (Fellows & Farah, 2005).”
Neural systems implicated in delayed and probabilistic reinforcement (2006, background): “…low-risk card decks that yield a net positive outcome and high-reward, high-risk decks that yield a net negative outcome, though the precise locus and nature of the deficit seen on this task is debated (Clark, Manes, Antoun, Sahakian, & Robbins, 2003; Fellows & Farah, 2005; Manes et al., 2002).”