Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task

By K. Bolla, D. Eldreth, E. London, Kent A. Kiehl, M. Mouratidis, C. Contoreggi, J. Matochik, V. Kurian, Jean-Lud Cadet, A. Kimes and 2 more. NeuroImage, 2003

580 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/f654c97f6a8d0c4957bb7f5c0c163cee357f30b2

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior (2010, unknown): “Decision-making dysfunction has been linked to other brain regions, including the medial and dorsolateral prefrontal cortices, in studies of other psychiatric conditions e.g. substance dependence (Bolla et al., 2003; Tanabe et al., 2007).”
Revealing Neurocomputational Mechanisms of Reinforcement Learning and Decision-Making With the hBayesDM Package (2016, methodology): “The IGT has been used extensively to study decision-making in several psychiatric populations (Ahn et al., 2014; Bechara & Martin, 2004; Bechara et al., 2001; Bolla et al., 2003; Grant, Contoreggi, & London, 2000; Vassileva, Gonzalez, Bechara, & Martin, 2007).”
The somatic marker hypothesis: a critical evaluation. (2006, methodology): “A subsequent PET study using a similar protocol in cocaine users (Bolla et al., 2003) allowed preliminary investigation of how this network is altered in groups who are impaired at behavioural acquisition of the IGT.”
Neurocircuitry of Addiction (2009, background): “…and delayed reward discounting that are mediated by the medial and orbital prefrontal cortices, as well as spatial, verbal, and recognition memory impairments that are mediated by the hippocampus, and these deficits can predict poor treatment outcomes (Aharonovich et al, 2006; Bolla et al, 2003).”
Insights into the neural basis of response inhibition from cognitive and clinical neuroscience. (2009, unknown): “, 2007), make riskier decisions on various gambling tasks (Bartzokis et al., 2000; Monterosso et al., 2001; Bolla et al., 2003; Fishbein et al., 2005; Verdejo-Garcia et al., 2008), and amphetamine users sample less of the available information prior to making decisions (Clark et al.”
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion (2005, result): “This is consistent with burgeoning neuroimaging and neuropsychological evidence from human studies suggesting that chronic drug abusers show deficits in tests of inhibitory control and decision makin”
Distinct neural mechanisms of risk and ambiguity: A meta-analysis of decision-making (2006, background): “Furthermore, populations with impaired decision-making demonstrate abnormalities in OFC, further confirming a link between OFC function and psychopathological states (Bechara and Damasio, 2002; Blair et al., 2001; Bolla et al., 2003; Mitchell et al., 2002).”