Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis.

By Gianfranco Bazzoni, E. Dejana. Physiological Reviews, 2004

1,363 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Neurology

View Paper: https://www.semanticscholar.org/paper/6b537cd7c582a7e71394b7672e6ddd88310c30aa

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Citations in the corpus

The blood-brain barrier in health and chronic neurodegenerative disorders. (2008, neutral): “Within the AJ, the endothelial-specific integral membrane protein VE-cadherin is linked to the cytoskeleton via catenins, which belong to the family of armadillo proteins (Bazzoni and Dejana, 2004).”
The role of adherens junctions and VE-cadherin in the control of vascular permeability (2008, background): “Adherens junctions and vascular integrity Previous work has described the molecular organization of the different types of endothelial cell-cell junctions, and has established a basis for understanding how these structures might crosstalk and reciprocally interact (Bazzoni and Dejana, 2004; Muller, ”
The Blood-Brain Barrier/Neurovascular Unit in Health and Disease (2005, background): “The interactions of TJ proteins with each other and with intracellular signaling pathways have been reviewed extensively elsewhere (Bazzoni and Dejana, 2004); as such, we limit our treatment here to pathways demonstrated to be involved in the regulation of TJ organization and function at the BBB…”
Cytokines in atherosclerosis: pathogenic and regulatory pathways. (2006, background): “The intercellular junction complex and its interactions with the cytoskeleton are important for the maintenance of endothelial permeability (43).”
VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity. (2013, neutral): “In some vessels, the endothelial cells express two other members of the cadherin family, P-cadherin and T-cadherin (Bazzoni and Dejana, 2004).”
Matrix Metalloproteinase-Mediated Disruption of Tight Junction Proteins in Cerebral Vessels is Reversed by Synthetic Matrix Metalloproteinase Inhibitor in Focal Ischemia in Rat (2007, background): “Tight junction proteins (TJPs) in endothelial cells are a major structural component of the blood–brain barrier (BBB) formed by components of the neurovascular unit (Ballabh et al, 2004; Bazzoni and Dejana, 2004).”
Signaling mechanisms regulating endothelial permeability. (2006, background): “-Catenin or plakoglobin then binds -catenin, which links the cadherin-catenin complex to the actin cytoskeleton (57).”
Reactive Oxygen Species in Inflammation and Tissue Injury (2014, neutral): “AJs are composed of the cadherin family of transmembrane adhesion proteins that are anchored to the cytoskeletal network by intermediate cytoplasmic proteins from the catenin family, including a-, b-, c-, and p120 catenins (31).”
The blood-brain barrier: an engineering perspective (2013, background): “Cell-cell adhesion is achieved through the formation of adherens junctions and tight junctions (Bazzoni and Dejana, 2004; Dejana, 2004; Aird, 2007).”
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. (2013, background): “by small GTPases such as Rho and Rac, or by cytochalasin D) (Bazzoni and Dejana, 2004; Harhaj and Antonetti, 2004; Spindler et al., 2010).”
ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signalling. (2010, background): “cular permeability; an effect seen in diseased vasculature with elaborated inflammatory mediators, including thrombin,(6) cytokines, and VE growth factor.(7) Moreover, the adherens junction participates in”