Signaling mechanisms regulating endothelial permeability.

By D. Mehta, Asrar B. Malik. Physiological Reviews, 2006

1,749 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ccf4e88bdb772bd7c916a5d678ec961b7a6ffb41

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Citations in the corpus

The role of adherens junctions and VE-cadherin in the control of vascular permeability (2008, background): “…Several studies focus on the effect of agents that increase vascular permeability on the organization of endothelial cell-cell junctions (Dudek and Garcia, 2001; Esser et al., 1998; Mehta and Malik, 2006; Schnittler, 1998; van Hinsbergh and van Nieuw Amerongen, 2002; Weis and Cheresh, 2005).”
ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signalling. (2010, background): “as well as in the mediation of responses to inflammatory stimuli such as thrombin.(4) As an important type of cell–cell junctions in the peripheral vascular endothelium, the adherens junction is mainly composed of VE-cadherin and catenins.”
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. (2013, background): “(NSF), syntaxin and soluble NSF-attachment protein (SNAP25; Klaassen et al., 2009; Mehta and Malik, 2006) (Fig.”
Regulation of retinal blood flow in health and disease. (2008, background): “Constitutive transcytosis of albumin across the vascular endothelium is particular in that each transcytotic routing, whether receptor-mediated, by adsorption or as bulk fluid, is implicated in regulating the transvascular oncotic pressure gradient of albumin (Minshall et al., 2003; Mehta and Malik,”
Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. (2011, background): “Adapted from Armulik et al. (2010). transendothelial permeability by inducing so-called vesiculotubular organelles (reviewed in Mehta and Malik, 2006).”
Reactive Oxygen Species in Inflammation and Tissue Injury (2014, positive): “The plasma protein albumin is actively transported by transcellular route by binding to a docking protein gp60 present in caveoli that transport it across the endothelium (284).”
Vascular Endothelial Cell Biology: An Update (2019, background): “The endothelium actively controls the degree of vascular relaxation/constriction, the extravasation of solutes, fluid, hormones, and macromolecules [11], as well as that of platelets and blood cells [12,13].”
Microvascular fluid exchange and the revised Starling principle. (2010, background): “Oedema can result from abnormal Starling’s forces, increased endothelial permeability (e.g. inflammation), or impaired lymphatic drainage.50 The biochemical processes mediating increases in endothelial permeability were reviewed recently by Mehta and Malik.85 Here, we consider the impact of relative”
Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. (2012, background): “Others have provided detailed, comprehensive reviews on transcapillary fluid exchange and Vi regulation (25, 96, 290, 292, 294, 387, 410, 460).”
In vitro microvessels for the study of angiogenesis and thrombosis (2012, positive): “15 0.05Þ × 10−6 cm s−1 for 70 kDa FITC-Dextran] (21), but close to those for isolated mammalian venules (approximately 2 × 10−6 cm s−1 for FITC-albumin) (22) and of endothelial monolayers formed in vitro [Oð10−6Þ −Oð10−5Þ cm s−1 for FITC-albumin] (7, 23).”
Cell Biology of Ischemia/Reperfusion Injury (2012, background): “Two major endothelial junctional complexes mediate paracellular permeability: (1) tight junctions characterized by intercellular linkage via extracellular, homophilic binding of the transmembrane proteins, occludin and claudin, whose intracellular domains are, in turn, linked to microfilaments of th”
The Blood-Testis Barrier and Its Implications for Male Contraception (2012, background): “protein endocytosis can be mediated by either clathrinor caveolae-dependent pathways or macropinocytosis (Tuma and Hubbard, 2003; Maxfield and McGraw, 2004; Mehta and Malik, 2006; Clague and Urbé, 2010; Golachowska et al., 2010; Hsu and Prekeris, 2010).”