The role of adherens junctions and VE-cadherin in the control of vascular permeability

By E. Dejana, F. Orsenigo, M. Lampugnani. Journal of Cell Science, 2008

991 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

ADAM15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity (2012, background): “A major determinant of endothelial paracellular permeability is the adherens junction composed of VE-cadherin, a transmembrane molecule that forms homophilic bonds on the cell surface with its intracellular segment facilitating connection to the actin-linking α-, β-, and γ-catenins and p120.(2) This”
The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction (2009, background): “The primary component of adherens junctions is vascular endothelial (VE)-cadherin, a Ca-regulated protein that mediates cell–cell adhesion via homophilic interactions between the extracellular domains of proteins expressed in adjacent cells [22].”
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. (2013, neutral): “ability (Dejana et al., 2008; Vestweber, 2008).”