Generation of pluripotent stem cells from neonatal mouse testis.

By M. Kanatsu-Shinohara, K. Inoue, Jiyoung Lee, M. Yoshimoto, N. Ogonuki, H. Miki, Shiro Baba, Takeo Kato, Y. Kazuki, S. Toyokuni and 8 more. Cell, 2004

830 citations recorded by the source corpus.

Subfields: Molecular Biology, Reproductive Medicine

View Paper: https://www.semanticscholar.org/paper/59de4e9e2f9991c964234d3a4334f296dc167aa8

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Citations in the corpus

Epigenetic reprogramming and induced pluripotency (2009, background): “The observation that in GS cells many pluripotency genes show demethylation but are not expressed might explain their tendency to spontaneously reprogram into mGS cells upon explantation (see Glossary, Box 1) (Imamura et al., 2006; Kanatsu-Shinohara et al., 2004; Seandel et al., 2007).”
Epigenetic events in mammalian germ-cell development: reprogramming and beyond (2008, background): “Notably, germline stem (GS) cells — which are established from neonatal testes, can be maintained stably in culture and can give rise to sperm when transplanted into testes — possess paternal methylation imprints, whereas their multipotent derivatives, mGS cells, show partial demethylation at these ”
Stem cell niche: structure and function. (2005, background): “Second, GDNF, a member of the TGF-β superfamily produced by Sertoli cells, can control GSC self-renewal and maintain GSCs in vitro (Kanatsu-Shinohara et al. 2004, Kubota et al. 2004).”
Naive and primed pluripotent states. (2009, background): “It is surely not a coincidence that germ cells can be reprogrammed to pluripotency in culture without genetic manipulation (Kanatsu-Shinohara et al., 2004; Matsui et al., 1992; Resnick et al., 1992).”
Somatic cell reprogramming and transitions between pluripotent states: facts, hypotheses, unresolved issues (2010, neutral): “Called male germ stem cells, these ES-like cells can be propagated in serum and LIF (Kanatsu-Shinohara et al., 2004).”
Induced pluripotency: history, mechanisms, and applications. (2010, background): “…al. 1992) have been derived from primordial germ cells (PGCs) of the midgestation embryo, and multipotent germline stem cells (mGSCs) have been generated from explanted neonatal (Kanatsu-Shinohara et al. 2004) and adult (Guan et al. 2006; Seandel et al. 2007; Ko et al. 2009) mouse testicular cells.”
Senescence impairs successful reprogramming to pluripotent stem cells. (2009, background): “The tumour suppressor p53 limits de-differentiation The p53 tumour suppressor was first linked to reprogramming when mouse germ cells deficient for p53, were shown to be able to give rise to ES-like cells (Kanatsu-Shinohara et al., 2004a).”