Epigenetic events in mammalian germ-cell development: reprogramming and beyond

By Hiroyuki Sasaki, Yasuhisa Matsui. Nature reviews genetics, 2008

876 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/55b3a00880ea5997bb238b57d9210e66fd8a438a

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In Molecular Biology

1. Yi Zhang
2. Hao Wu
3. Wolf Reik
4. W. Dean
5. Jörn Walter
6. Felix Krueger
7. Fátima Santos
8. Simon R. Andrews

Citations in the corpus

• Dynamic CpG island methylation landscape in oocytes and preimplantation embryos (2011, background): “864" language="eng" relation="no"> Elucidating how and to what extent CpG islands (CGIs) are methylated in germ cells is essential to understand genomic imprinting and epigenetic reprogrammin”
• Prenatal environmental exposures, epigenetics, and disease (2011, positive): “Imprints are established perinatally in the male germ line and are maintained throughout the mitotic divisions of the spermatogonial stem cells [20,21,48].”
• Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions (2014, positive): “5, a subset of posterior epiblast cells ( 40 cells) are instructed by specific factors such as BLIMP1 (also known as PRDM1) and PRDM14 to become PGCs (Sasaki and Matsui, 2008).”
• The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells (2012, background): “Epigenetic information in the mammalian genome is relatively stable in differentiated cells of the soma but is reprogrammed on a genome-wide scale in primordial germ cells (PGCs) and early embryos (Reik et al., 2001; Surani et al., 2007; Sasaki and Matsui, 2008; Smith et al., 2012).”
• 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. (2011, background): “The reprogramming of DNA methylation has a direct influence on genomic imprints, the regulation of pluripotency and stem cell networks, the erasure of epimutations and the transcriptional control of transposon”
• DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos (2014, background): “The establishment of germ cell-specific methylation marks after PGC reprogramming occurs at different times and in different cellular environments in males and females, ultimately leading to sperm- and oocyte-specific patterns (Sasaki and Matsui 2008; Saitou and Yamaji 2012).”
• Epigenetics and the environment: emerging patterns and implications (2012, result): “This suggests that, in contrast to the germ lines in mammal”