The plasticity of dendritic cell responses to pathogens and their components.

By Qian Huang, Dongyu Liu, P. Majewski, Leah C. Schulte, Joshua M. Korn, Richard A. Young, Eric S. Lander, Nir Hacohen. Science, 2001

793 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/2f1b50024a0e0510015116a46b4a46ac3c8afb0b

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In Immunology

1. R. Medzhitov
2. Shizuo Akira
3. T. Mogensen
4. B. Beutler
5. Yong‐jun Liu
6. A. Iwasaki
7. M. Kapsenberg
8. K. Shortman

Citations in the corpus

• Toll-like receptor control of the adaptive immune responses (2004, background): “Activation of TLRs induces the expression of selectin, chemokine and chemokine receptor genes that regulate cell migration to the sites of inflammatio”
• Mouse and human dendritic cell subtypes (2002, background): “Exposure of such monocyte-derived DCs to different pathogens has been shown to cause extensive changes in gene-expression patterns, emphasizing the extent of DC adaptabilit”
• Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens (2010, background): “coli SD54 almost completely overlaps with the response induced by its hexa-acyl LP”
• The Toll and Imd pathways are the major regulators of the immune response in Drosophila (2002, background): “Importantly, different pathogens elicit speci®c transcription programmes that can now be investigated by using microarray technology (De Gregorio et al., 2001; Huang et al., 2001; Irving et al., 2001).”
• Mediators of Chronic Obstructive Pulmonary Disease (2004, background): “Dendritic cells can activate a variety of other inflammatory and immune cells, including macrophages, neutrophils, and T and B lymphocytes (Huang et al., 2001).”
• How we detect microbes and respond to them: the Toll‐like receptors and their transducers (2003, methodology): “It has been shown [ 63 ] that LPS induces most of the transcriptional responses in dendritic cells (DCs), which are induced by intact Escherichia coli organisms.”
• Immunity to fungal infections (2011, background): “albicans proved to be a useful pathogen model to dissect events that occur at the fungus–DC interfac”
• Dendritic-cell control of pathogen-driven T-cell polarization (2003, background): “So far, such analyses have indicated that groups of pathogens, their components or the tissue factors they elicit, induce highly variable gene profiles in DC”
• MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells (2009, background): “Because gene expression of proinflammatory cytokines is transient and is limited to the early phase of DC maturation (23), transcription levels of the proinflammatory genes identified upon miR-155 knockdown were monitored in activated Fig.”
• Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses (2009, background): “ulated through induced expression of cell adhesion molecules and integrins in response to PRR activation (141, 151, 204).”