Mouse and human dendritic cell subtypes

By K. Shortman, Yong‐jun Liu. Nature reviews. Immunology, 2002

2,591 citations recorded by the source corpus.

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Citations in the corpus

Tolerogenic dendritic cells and the quest for transplant tolerance (2007, background): “The initial misconception that mouse CD8α + DCs were derived exclusively from lymphoid-committed haematopoietic precursors, whereas CD8α − DCs arose only from myeloid-restricted precursors, led to the designation of CD8α + and CD8α − DCs as lymphoid- and myeloid-related DCs, respectivel”
Notch–RBP-J signaling controls the homeostasis of CD8− dendritic cells in the spleen (2007, background): “In the steady state, the DC system comprises resident tissue DCs, immature blood-derived DCs in the lymphoid organs, and activated DCs migrating from the tissues into lymph nodes (2).”
Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens (2004, background): “However, DCs are heterogeneous (82, 83), and to fully elucidate the mechanistic basis of priming, it is necessary to identify the precise subset(s) involved in presentation of each antigen or pathogen type.”
Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. (2008, background): “Two major DC subtypes are recognized: the myeloid DCs (mDCs) and the plasmacytoid DCs (pDCs) (Banchereau et al., 2000; Shortman and Liu, 2002).”
DC-SIGN Is the Major Mycobacterium tuberculosis Receptor on Human Dendritic Cells (2003, background): “As reported (24), human monocyte-derived DCs (MDDCs; reference 25) expressed high levels of DC-SIGN together with CR3 and MR.”
Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. (2002, background): “We next asked mouse mature DC subsets, characterized by CD11c and various levels of B220, Gr-1, Mac-1, and CD4 (del whether constitutive overexpression of the antiapoptotic gene, bcl-2, would counteract the effect of TACI- Hoyo et al., 2002; Asselin-Paturel et al., 2001; Shortman and Liu, 2002).”
Steady-state and inflammatory dendritic-cell development (2007, background): “, it has become evident that there are many distinct DC subtypes, each with a particular location and specialized function in the immune syste”