Lymphoid organ development: from ontogeny to neogenesis

By Danielle L. Drayton, S. Liao, R. Mounzer, N. Ruddle. Nature Immunology, 2006

790 citations recorded by the source corpus.

Subfields: Immunology, Oncology, Physiology

View Paper: https://www.semanticscholar.org/paper/2a3f6764c9157939454d8493c96a653114a385b6

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. R. Medzhitov
2. C. Sautès-Fridman
3. H. Spits
4. W. Fibbe
5. T. Tammela
6. N. Crellin
7. K. Alitalo
8. Shizuo Akira

In Oncology

1. K. Alitalo
2. T. Tammela
3. C. Sautès-Fridman
4. J. Pober
5. R. Medzhitov
6. W. Sessa
7. Rakesh K. Jain
8. M. Shibuya

In Physiology

1. T. Tammela
2. K. Alitalo
3. R. Medzhitov

Citations in the corpus

• Presence of B cells in tertiary lymphoid structures is associated with a protective immunity in patients with lung cancer. (2014, background): “rejection (24), are transient lymphoid structures induced on chronic inflammation in nonlymphoid tissues.”
• Origin and physiological roles of inflammation (2008, background): “If the combined effect of these cells is still insufficient, a chronic inflammatory state ensues, involving the formation of granulomas and tertiary lymphoid tissue”
• Evolving functions of endothelial cells in inflammation (2007, background): “Additional endothelial cell responses occur as chronically inflamed tissues acquire the characteristics of a secondary lymphoid organ, sometimes referred to as tertiary lymphoid organs (TLOs”
• Lymphangiogenesis: Molecular mechanisms and future promise. (2010, background): “express interleukin-7-receptor-α (IL-7Rα), CD45, and CD4 but lack CD3 (Drayton et al., 2006; Mebius, 2003).”
• CD4+T Cells: Differentiation and Functions (2012, background): “Mature naı̈ve CD4+ T cells are then deployed to secondary lymphoid organs, including the spleen, lymph nodes, and the mucosaassociated lymphoid tissue, where they constantly survey for pMHC II molecules, for antigen recognition [10].”
• Long-term survival for patients with non-small-cell lung cancer with intratumoral lymphoid structures. (2008, background): “The de novo formation of ectopic lymphoid structures (also called tertiary lymphoid structures) at the site of inflammation can arise in potentially all inflamed noncanonical lymphoid organs.(4) Bronchusassociated lymphoid tissues (BALTs) have been described in the human fetus and infant lung.”
• Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells (2009, background): “1668" language="eng" relation="no"> Lymph nodes optimize the efficiency of immunological responses by providing an environment that increases the chances that naive circulating lymphocytes will encounter their cognate antigen and, once this has occurred, by facilitating the activation and s”