Long-term survival for patients with non-small-cell lung cancer with intratumoral lymphoid structures.

By M. Dieu-Nosjean, M. Antoine, C. Danel, D. Heudes, M. Wislez, V. Poulot, N. Rabbe, L. Laurans, E. Tartour, L. de Chaisemartin and 3 more. Journal of Clinical Oncology, 2008

933 citations recorded by the source corpus.

Subfields: Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/b6686b5ad4e50920b612442c54be7a4ac5258691

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Citations in the corpus

T Cell Dysfunction in Cancer (2018, background): “The occurrence of TLS is often associated with a favorable prognosis (Dieu-Nosjean et al., 2008; Sautes-Fridman et al., 2016) and frequently correlates with high overall T cell infiltration and lower macrophage infiltration (Lavin et al., 2017; Poschke et al., 2016).”
Roles of the immune system in cancer: from tumor initiation to metastatic progression (2018, background): “For example, high levels of tumor-infiltrated T cells correlate with good prognosis in many solid cancers (Clemente et al. 1996; Oldford et al. 2006; Dieu-Nosjean et al. 2008); on the other hand, high levels of macrophage infiltration correlate with a worse prognosis (Zhang et al. 2012; Figure 1.”
Immune infiltration in human tumors: a prognostic factor that should not be ignored (2010, background): “Similarly, in early stage NSCLC, the density of mature DCs, which home exclusively in the T-cell areas of tertiary lymphoid structures, was highly associated with a favorable clinical outcome (Dieu-Nosjean et al., 2008).”
Presence of B cells in tertiary lymphoid structures is associated with a protective immunity in patients with lung cancer. (2014, methodology): “Density of Follicular B Cells Correlates with Long-Term Survival, and a Synergistic Effect Is Observed When Combined with Mature DC Density Because the density of mature DCs was shown to be associated with a favorable prognosis in patients with NSCLC (23), we investigated correlations between follic”
Clinical significance of tumor-infiltrating lymphocytes in breast cancer (2016, background): “Infiltration of immune cells, particularly infiltration of anti-tumor type 1 lymphocytes, has predicted improved prognosis in many different tumor types including colon, ovarian, lung and breast cancer [1–4].”
CD4⁺ follicular helper T cell infiltration predicts breast cancer survival. (2013, neutral): “indicator for TLS (26), and in colorectal cancer, in which both lymphocyte aggregates (57) and active TLS, the latter identified and SN+S–treated donor cells in parallel with a decrease in JUN, FOSB, and ATF3 in the rested TIL, suggesting that their expression is induced when activated cells enter t”
The immune contexture in human tumours: impact on clinical outcome (2012, background): “B cells are mostly found in the invasive margin of growing tumours and in TLS that are adjacent to tumour bed”
Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents. (2015, background): “In line with this notion, the presence of TLOs and specific DC subsets within neoplastic lesions constitute a positive prognostic feature for patients with cancer (Dieu-Nosjean et al., 2008; Senovilla et al., 2012a).”