HMGB1 and RAGE in inflammation and cancer.

By G. Sims, D. C. Rowe, S. Rietdijk, R. Herbst, A. Coyle. Annual Review of Immunology, 2010

1,447 citations recorded by the source corpus.

Subfields: Clinical Biochemistry, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/2a17b49a238fc0365758a81b8f87b69b5c396048

How researchers see this paper

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In Clinical Biochemistry

1. D. Tang
2. R. Kang
3. Michael Lotze
4. H. J. Zeh
5. Kevin J. Tracey
6. M. Bianchi
7. Peter Vandenabeele
8. J. Martinou

In Immunology

1. Guido Kroemer
2. L. Galluzzi
3. L. Zitvogel
4. Simone Fulda
5. D. Tang
6. R. Kang
7. Junying Yuan
8. Oliver Kepp

In Molecular Biology

1. Guido Kroemer
2. Douglas R. Green
3. L. Galluzzi
4. D. Tang
5. R. Kang
6. Beth Levine
7. Simone Fulda
8. Brent R. Stockwell

Citations in the corpus

• Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018, background): “In particular, the ligation of HGMB1 to TLR4 on DCs promotes antigen processing and cross-presentation, yet does not induce DC maturation, which is mainly stimulated by RAGE [870, 916].”
• IL-6 in inflammation, immunity, and disease. (2014, background): “The S100 family of proteins comprises more than 25 members, some of which also interact with RAGE to evoke sterile inflammation (Sims et al. 2010).”
• Progress Towards Biocompatible Intracortical Microelectrodes for Neural Interfacing Applications (2014, background): “glycosylphosphatidylinositol-anchored membrane glycoprotein), and other receptor-mediated pathways [119, 120].”
• PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity (2012, background): “RAGE is linked functionally to outcome in several infectious diseases including cancer, diabetes, and Alzheimer’s disease (199, 202).”
• Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy (2022, background): “The inhibition of tumor growth by blocking HMGB1 and RAGE signaling was observed in a murine lung cancer model.(229) In addition to RAGE receptors, HMGB1 signaling acts on neutrophils, monocytes, macrophages, etc.”
• Endogenous HMGB1 regulates autophagy (2010, background): “, 2008), and its critical role as a universal DNA sensor (Yanai et al., 2009; Sims et al., 2010), we propose a more nuanced conceptual model involving HMGB1 and cell death.”