γ‐Aminobutyric acid production by culturable bacteria from the human intestine

By E. Barrett, R. Ross, P. O’Toole, G. FitzGerald, C. Stanton. Journal of Applied Microbiology, 2012

1,111 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/299f698e01d30f7e0a651c964e2c213c3f2a3195

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. J. Cryan
2. Ted G. Dinan
3. G. Clarke
4. C. Stanton
5. P. Kennedy
6. R. Stilling
7. Yan Wang
8. L. Kasper

In Plant Science

1. J. Cryan
2. Ted G. Dinan

Citations in the corpus

• Minireview: Gut microbiota: the neglected endocrine organ. (2014, background): “For example, -aminobutyric acid (GABA), the most important inhibitory transmitter in the brain is produced by several lactobacilli (10), whereas monoamines such as noradrenaline, dopamine, and serotonin are also produced by certain strains of bacteria (11, 12) (See Table 2).”
• The role of microbiome in central nervous system disorders (2013, positive): “For example, B. longum NCC3001 can normalize murine hippocampal BDNF expression and L. rhamnosus (JB-1) can exert differential regulation of GABA transcription in different CNS regions (Bercik et al., 2011b; Bravo et al., 2011).”
• Role of Lactobacillus reuteri in Human Health and Diseases (2018, background): “L. reuteri can also produce gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system (Su et al., 2011; Barrett et al., 2012; Pallin et al., 2016).”
• Gut microbes promote colonic serotonin production through an effect of short‐chain fatty acids on enterochromaffin cells (2015, background): “, SCFAs) that potentially affect serotonergic regulation (11, 30, 31), and pathogenic strains of E.”
• Psychobiotics: a novel class of psychotropic. (2013, background): “We have recently reported the ability of intestinally derived strains of lactobacilli and bifidobacteria to produce GABA from monosodium glutamate (11).”
• Stress & the gut-brain axis: Regulation by the microbiome (2017, neutral): “Thus, additional signaling pathways are likely involved in microbiota e brain e gut communication (Barrett et al., 2012).”
• Control of Brain Development, Function, and Behavior by the Microbiome (2015, neutral): “A uthor M anuscript A uthor M anuscript A uthor M anuscript A uthor M anuscript intestinally-derived (and therefore likely microbiota-derived) production of these molecules may instead act locally on the vagus nerve, or through signaling via the periphery (Barrett et al., 2012).”