Psychobiotics: a novel class of psychotropic.
By Ted G. Dinan, C. Stanton, J. Cryan. Biological Psychiatry, 2013
1,176 citations recorded by the source corpus.
Subfields: Gastroenterology, Pharmacy, Physiology
View Paper: https://www.semanticscholar.org/paper/9459fc54a7a2147ed5f958998d61048e805a04b8
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Citations in the corpus
- Altered fecal microbiota composition in patients with major depressive disorder. (2015, background): “Accumulating evidence from animal studies supports the hypothesis that gut microbiota play an important role in central nervous system function, namely through inflammation, and the hypothalamic–pituitary–adrenal (HPA) axis, and by affecting neurotransmission (Bangsgaard Bendtsen et al., 2012; Colli”
- Gut Microbes and the Brain: Paradigm Shift in Neuroscience (2014, background): “However, even within bacterial genera, marked strain differences occur, and only a few strains have any positive effects (Dinan et al., 2013).”
- Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018, background): “In humans, psychobiotics, a class of probiotics with antiinflammatory effects might be useful to treat patients with psychiatric disorders due to their antidepressive and anxiolytic effects (133).”
- Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour. (2015, background): “, 2012), but also in the treatment of psychiatric conditions (Dinan, 2013).”
- Inflammation: depression fans the flames and feasts on the heat. (2015, background): “Early-life maternal separation in mice can produce both long-lasting changes in HPA stress responses as well as persistent microbiome alterations (57), evidence for one pathway through which early adversity induces depression and inflammatory responses in adults.”
- Kynurenine pathway metabolism and the microbiota‐gut‐brain axis (2017, background): “Developing ‘psychobiotics’ with precise kynurenine modulating capabilities could be an interesting option in this regard (Dinan et al., 2013).”
- Microbial genes, brain & behaviour – epigenetic regulation of the gut–brain axis (2014, background): “Psychobiotic: A concept recently introduced by Dinan, Stanton and Cryan defines psychobiotics – analogous to probiotics – as live organisms that produce positive effects on mental health (Dinan et al. 2013).”
- Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders (2015, background): “The term “psychobiotics” has been recently conceived to encompass the sub-types of probiotics that may be capable of modulating the brain-gut-microbiota axis to have a beneficial effect on mood, anxiety and cognition (Dinan et al., 2013).”
- Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut (2016, background): “Moreover, interest is growing to use bifidobacterial strains (such as Bifidobacterium infantis 35624) as psychobiotics, which are “live organisms that, when ingested in adequate amounts, produce a health benefit in patients suffering from psychiatric illness” (Dinan et al., 2013, 2015).”
- Stress & the gut-brain axis: Regulation by the microbiome (2017, background): “The concept of psychobiotics, bacteria with positive effects on mental health, was coined in 2013 (Dinan et al., 2013) and has recently been expanded to include other microbiota-targeted interventions that can positively modify mental health including in healthy volunteers (Sarkar et al., 2016).”
- Minireview: Gut microbiota: the neglected endocrine organ. (2014, background): “An extension of this concept is the promise of psychobiotics to exert beneficial psychotropic effects (188).”