Becoming a new neuron in the adult olfactory bulb

By A. Carleton, Leopoldo T. Petreanu, Rusty Lansford, Arturo Alvarez-Buylla, Pierre Marie Lledo. Nature Neuroscience, 2003

847 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Neurology, Sensory Systems

View Paper: https://www.semanticscholar.org/paper/1d64f176e133356c18ee97fe06fb006eaf480d0d

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Citations in the corpus

Interneurons Produced in Adulthood Are Required for the Normal Functioning of the Olfactory Bulb Network and for the Execution of Selected Olfactory Behaviors (2009, background): “…(Lledo and Saghatelyan, 2005), establish dendrodendritic synapses with the OB principal cells (Whitman and Greer, 2007), display appropriate electrophysiological features (Belluzzi et al., 2003; Carleton et al., 2003), and respond to odor stimulations (Carlén et al., 2002; Magavi et al., 2005).”
Fragile X Mental Retardation Protein Regulates New Neuron Differentiation in the Adult Olfactory Bulb (2011, methodology): “In the adult olfactory bulb (OB), newly generated neurons exhibit stereotyped morphological and electrophysiological hallmarks of differentiation and incorporation into synaptic circuits (Petreanu and Alvarez-Buylla, 2002; Carleton et al., 2003).”
High Levels of Id1 Expression Define B1 Type Adult Neural Stem Cells (2009, background): “Adult neu- rogenesis generates new neurons that integrate into existing neural circuitry (Carleton et al., 2003; Paton and Nottebohm, 1984; van Praag et al., 2002).”
Sox1 marks an activated neural stem/progenitor cell in the hippocampus (2012, background): “NSCs in the V-SVZ contribute to migrating neuroblasts along the rostral migratory stream that go on to become interneurons within the olfactory bulb (Luskin, 1993; Lois and Alvarez-Buylla, 1994; Petreanu and Alvarez-Buylla, 2002; Carleton et al., 2003).”
Distinct Mammalian Precursors Are Committed to Generate Neurons with Defined Dendritic Projection Patterns (2007, neutral): “C). The membrane capacitance of deep branching cells was larger than that of the superficial cells, most likely due to their differences in membrane surface. In summary, these data confirm that the new neurons with deep and superficial dendritic targeting not only shared a common morphology, but bot”
Pattern separation: a common function for new neurons in hippocampus and olfactory bulb (2011, positive): “Interestingly, adult-born cells synapse on to all major cell types in the OB (Bardy et al., 2010; Carleton et al., 2003; Panzanelli et al., 2009).”
Is adult neurogenesis essential for olfaction? (2011, neutral): “23 43 Carleton, A. et al. (2003) Becoming a new neuron in the adult olfactory bulb.”
Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb (2013, background): “Because at this stage some of the starter population of cells was still found along the RMS or entering the OB, it is tempting to speculate that these presynaptic neurons form transient synapses with migrating newborn neurons, possibly supplying neurotransmitters during, and thereby affecting their ”
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain (2005, background): “…migratory neuroblasts (A cells) which then join the rostral migratory stream to reach their final destination in the olfactory bulb where they differentiate into functional interneurons (Lois and Alvarez-Buylla, 1994; Doetsch et al., 1999; Alvarez-Buylla et al., 2002; Carleton et al., 2003).”
Adult neurogenesis: from precursors to network and physiology. (2005, methodology): “Less frequently, retroviral tracing has also been used for “developmental” studies (81, 123, 439, 501).”
Adult neurogenesis and the olfactory system. (2009, background): “The delay in spiking ability relative to synaptic inputs is unique to the development of adult-born cells in olfactory bulb (Carleton et al., 2003).”
A hypothesis about the role of adult neurogenesis in hippocampal function. (2004, background): “Growing evidence indicates that new neurons become functionally integrated in the existing circuits (2, 4, 16, 39, 52), although the true physiological relevance of adult neurogenesis remains unknown.”
Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells (2006, background): “Neurogenesis has been confirmed and further investigated electrophysiologically in the hippocampus (van Praag et al. 2002) and the olfactory bulb (Carleton et al. 2003; Magavi et al. 2005) by labelling the dividing cells with retroviruses.”