The dynamin superfamily: universal membrane tubulation and fission molecules?

By Gerrit J. K. Praefcke, H. McMahon. Nature reviews. Molecular cell biology, 2004

1,452 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0e0d766fa8e11786886a6c07674ce05dbf2e9e14

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Citations in the corpus

The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells. (2008, background): “The archetypal family member, dynamin, which is required for endocytosis (van der Bliek and Meyerowitz, 1991; van der Bliek et al., 1993), wraps around constrictions at the necks of vesicles that are budding from the plasma membrane (Hinshaw, 2000; Praefcke and McMahon, 2004).”
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β (2008, background): “Dynamin GTPases regulate endocytosis by controlling the 'pinching off' of plasma membrane invaginations, which creates early endosome”
Mitochondrial fusion and fission in mammals. (2006, background): “Other dynamin family GTPases have been shown to assemble into oligomers, and mutants with truncations or point mutations often have dominant-negative activity (Praefcke & McMahon 2004).”
Virus Entry by Endocytosis (2013, positive): “Dynamin has been shown to be indispensable in caveolar pathway [23, 63].”
Mitochondrial fusion and fission in cell life and death (2010, background): “These spirals are thought to sever the enclosed membranes following GTP hydrolysis through the mechanoenzymatic activity of dynami”
FtsZ and the division of prokaryotic cells and organelles (2005, background): “Another possibility is that the rapid net loss of FtsZ monomers, which are tethered to the membrane by the other proteins of the machine, exerts a pinching force on the membrane that is analogous to the mechanical force exerted by DYNAMINS on their membrane substrate”
Harnessing actin dynamics for clathrin-mediated endocytosis (2006, background): “In mammalian cells, dynamin is essential for the scission of clathrin-coated vesicle”
Mechanisms of membrane fusion: disparate players and common principles (2008, background): “Members of this family of proteins are large, self-oligomerizing GTPases that mediate membrane remodelling events such as endocytic vesicle scissio”
A Comprehensive Model for the Cellular Uptake of Cationic Cell‐penetrating Peptides (2007, background): “Dynamins couple to a large number of cellular signaling processes (51), and even though it is not clear why the peptides induce the formation of outward protrusions, dynamins could well be involved in such a process.”
Dynasore, a cell-permeable inhibitor of dynamin. (2006, background): “These and other observations have influenced the various models proposed to explain the role of dynamin in clathrin-coated vesicle fission (reviewed by Kelly [1999], Kirchhausen [1999], McNiven [1998], Sever et al. [2000b], Yang and Cerione [1999], Orth and McNiven [2003] , Praefcke et al. [2004], ”
Mitochondrial fission in apoptosis (2005, background): “Fission through 'drawstring' constriction? During endocytosis of synaptic vesicles, dynamin wraps around the necks of nascent invaginating pits in a spiral-like manner, and is thought to mediate both elongation of the pits into tubules and the final scission event to free the internalizing vesicle ”